Protein Info for ABIE53_004708 in Paraburkholderia graminis OAS925

Annotation: transcriptional regulator with PAS, ATPase and Fis domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 491 PF08448: PAS_4" amino acids 27 to 119 (93 residues), 34.1 bits, see alignment E=8.2e-12 PF00158: Sigma54_activat" amino acids 162 to 329 (168 residues), 216.3 bits, see alignment E=6.5e-68 PF14532: Sigma54_activ_2" amino acids 162 to 333 (172 residues), 74.9 bits, see alignment E=2.3e-24 PF07728: AAA_5" amino acids 184 to 302 (119 residues), 22.6 bits, see alignment E=2.8e-08 PF02954: HTH_8" amino acids 447 to 486 (40 residues), 35.4 bits, see alignment 2.1e-12

Best Hits

KEGG orthology group: None (inferred from 94% identity to bug:BC1001_4820)

Predicted SEED Role

"Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (491 amino acids)

>ABIE53_004708 transcriptional regulator with PAS, ATPase and Fis domain (Paraburkholderia graminis OAS925)
MMNDWAGLPAIYGDVLRRAMDSLFRTFENFSEGTFIVDADARVVWINKRYAARFGFADPE
QAIGRDCEAVIPNSLMREVVKTGKPILLDILETDREPLVVTRLPLKDDAGATVGAVGFAL
FDELKALTPLFSHYSRVQEELIATRQSLAQARRAKYTFGSFVGTSAASLEVKRQARRAAQ
LESPVLLLGETGTGKELLAHAIHGGSARANQPLVTVNVAAIPDTLLEVEFFGAAPGAYTG
ADRKGRVGKFELANGGTLFLDEIGDMPLPLQGKLLRVLQDKEFEPLGSNRIVRADVRIIA
ATSADLPALVAAGRFRADLFYRLNVLTIHAPPLRERTSDIEALAYAMLEDLSTQARGGSH
YELQDDALRLLCSYAWPGNVRELRNTLERAVMLSDSERIDARALAPFIGSGQSGAQGATA
QTPDGSSQTAASGADAAREPSSWSDAMAAFEKRFLSDALRANGGRVIETAAQIGMGRATL
YKKIAAHGIQV