Protein Info for ABIE53_004215 in Paraburkholderia graminis OAS925

Annotation: cytochrome c biogenesis protein CcdA/thiol-disulfide isomerase/thioredoxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 633 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 40 to 64 (25 residues), see Phobius details amino acids 70 to 89 (20 residues), see Phobius details amino acids 122 to 149 (28 residues), see Phobius details amino acids 157 to 179 (23 residues), see Phobius details amino acids 199 to 218 (20 residues), see Phobius details PF02683: DsbD" amino acids 7 to 195 (189 residues), 41 bits, see alignment E=5.3e-14 PF08534: Redoxin" amino acids 332 to 444 (113 residues), 52.8 bits, see alignment E=9.8e-18 PF00578: AhpC-TSA" amino acids 333 to 437 (105 residues), 49.8 bits, see alignment E=8.1e-17 PF13905: Thioredoxin_8" amino acids 340 to 435 (96 residues), 36.2 bits, see alignment E=1.6e-12 PF17991: Thioredoxin_10" amino acids 487 to 633 (147 residues), 167.4 bits, see alignment E=7.3e-53

Best Hits

KEGG orthology group: None (inferred from 57% identity to bam:Bamb_5960)

Predicted SEED Role

"DipZ protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (633 amino acids)

>ABIE53_004215 cytochrome c biogenesis protein CcdA/thiol-disulfide isomerase/thioredoxin (Paraburkholderia graminis OAS925)
MLLTLLAFAGGMLTILSPCILPVVPLVFARVDQSFVRHGVPLLAGMALTFAAVASLAVAG
GAWVAHVNEYGRWIALAFFAVFGASLLFPSMAERLTHPLVNLGNRLDGAVRRDGGEPRVM
SSVVLGVATGLLWAPCAGPILGLVMTGVILHRPGGAGVLPLLAFAAGAAASLAIVLAIGG
RVVASLRRSYAVSERVRQVLGAAVVLSAAAIALGFDTRVLALLPSLNTTGIEEKLVQRWS
PRAGSRGVQAEKVNAQQVDSKAGDSQAADSQAADSQAMNAEQPNAGALLKVSMTAEPAAA
TNPVPAAAKLSLPAEGAMPSLSGAVDWLNSPPLKTSDLRGKVVIVNFWTYSCINCLRTLP
YLKAWSNRYRDQGLVVIGVHAPEFAFEHNIANVKRAAADLHIDYPIAIDNKLAVWQAFDN
QYWPAFYIVDARGEIRYHHFGEGGYDESEQVIRQLLADAGHSKLPASAGAAKASGVEAAA
DPQDLRSGETYVGYRQAEGFASPETLAPDMLRAYSSPARLRTGSWSLDGEWNVAGERAQS
GASGAKIAYRFHARDLHLVLGPMADGKPVRFRVTLDGKPPGASHGADTDANGVGVVDKER
LYQLVRQSGAVQDRTFEIEFLDAGASAYAFTFG