Protein Info for ABIE53_003880 in Paraburkholderia graminis OAS925

Annotation: 2-keto-3-deoxygluconate permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 385 transmembrane" amino acids 74 to 92 (19 residues), see Phobius details amino acids 103 to 124 (22 residues), see Phobius details amino acids 137 to 157 (21 residues), see Phobius details amino acids 163 to 181 (19 residues), see Phobius details amino acids 201 to 223 (23 residues), see Phobius details amino acids 229 to 249 (21 residues), see Phobius details amino acids 256 to 276 (21 residues), see Phobius details amino acids 282 to 305 (24 residues), see Phobius details amino acids 316 to 337 (22 residues), see Phobius details amino acids 348 to 371 (24 residues), see Phobius details PF03812: KdgT" amino acids 65 to 373 (309 residues), 393 bits, see alignment E=5.2e-122

Best Hits

Swiss-Prot: 66% identical to KDGT_CARHZ: 2-keto-3-deoxygluconate permease (kdgT) from Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)

KEGG orthology group: K02526, 2-keto-3-deoxygluconate permease (inferred from 97% identity to bmj:BMULJ_05426)

MetaCyc: 54% identical to 2-dehydro-3-deoxy-D-gluconate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-113

Predicted SEED Role

"2-keto-3-deoxygluconate permease (KDG permease)" in subsystem D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (385 amino acids)

>ABIE53_003880 2-keto-3-deoxygluconate permease (Paraburkholderia graminis OAS925)
MISDTPPPRLPNSQSAVLITSIIKMSDLRKSADRSTLGHDRFNQKSDRSDQNPIRAETGM
AQINIKRGIERVPGGMMIVPLLLGALVATFLPGMPKFFGSFTNALFTGALPILAVFYVCM
GASIDVKATPYLLKKGGALFVTKVGAAIVVGVVMGHFLGEQPISSGLFAGLSTLAVVAAM
NDTNGGLYMALMGQYGRSEDVGAYTIMSLESGPFLTMVTLGVAGLSAFPWPTLVGSILPL
VFGMLLGNLDREMRAFLGKAVPVMIPFFALALGASLDLHKVWQAGVLGIGLGIAVVIVTG
IPLYLADRLTGGTGVAGTAAANTAGNAAAVPALIAAANPVYAEAAKSATLLVAACVVVTA
ILSPILTAAVAKRVQVRRESRELAR