Protein Info for ABIE53_003877 in Paraburkholderia graminis OAS925

Annotation: DeoR/GlpR family transcriptional regulator of sugar metabolism

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 278 PF08279: HTH_11" amino acids 6 to 42 (37 residues), 21.5 bits, see alignment 2.6e-08 PF08220: HTH_DeoR" amino acids 6 to 57 (52 residues), 53.9 bits, see alignment 1.9e-18 PF00455: DeoRC" amino acids 75 to 232 (158 residues), 144.8 bits, see alignment E=3.4e-46

Best Hits

Swiss-Prot: 35% identical to YULB_BACSU: Uncharacterized HTH-type transcriptional regulator YulB (yulB) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 93% identity to bgf:BC1003_0575)

Predicted SEED Role

"Transcriptional regulator of rhamnose utilization, DeoR family" in subsystem L-rhamnose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (278 amino acids)

>ABIE53_003877 DeoR/GlpR family transcriptional regulator of sugar metabolism (Paraburkholderia graminis OAS925)
MKASERHRAILELVLTGDANVEQLSAALGVSEATVRRDLTTLANQRRLVRTYGGATALIG
SHEPEASLEERKATQRDQKEAIARAAAAHVHDGDTVLLDGGTTCAALARHLGSRADLHVV
TNNLLAVMTLANAPGVHLTLIGGDLRNSSMSTVGPLAELSLSRLSVDKAFLGADGVVAGF
GLCEASAQQAYLKDCIIRRAAQVIVLADADKLGRSRQQHWTPLERDWRLITSSVADEACL
APFRALQRVVVETADLENAPLAATPREAAVRGTGVARD