Protein Info for ABIE53_003561 in Paraburkholderia graminis OAS925

Annotation: exoribonuclease-2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 706 PF00773: RNB" amino acids 242 to 470 (229 residues), 116 bits, see alignment E=1.2e-37 amino acids 479 to 520 (42 residues), 37.8 bits, see alignment 7.3e-14

Best Hits

KEGG orthology group: K01147, exoribonuclease II [EC: 3.1.13.1] (inferred from 94% identity to bug:BC1001_3059)

Predicted SEED Role

"Exoribonuclease II (EC 3.1.13.1)" in subsystem RNA processing and degradation, bacterial (EC 3.1.13.1)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 3.1.13.1

Use Curated BLAST to search for 3.1.13.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (706 amino acids)

>ABIE53_003561 exoribonuclease-2 (Paraburkholderia graminis OAS925)
MNVFFEESGSFKAGSVLSRQGDAFQVELPGGRRAKVRAKDVLIEFDKPGAAELMQEADAV
AQDIDLDFLWECAPDDEFPFATLGAEYFGERFGPTERAALVLRMHGAPVYFRRKGRGMYQ
RAPQEQLKMALAGLERKRQQALIQQGYEEELKAGRLPEAFTGKTALALLTKPDKNTIEYK
ALEAAAAARGISQARLMLECGAIPSARALHEARFLAEFFPHGTGFPPVTLGSLPDDLPEA
NVQAFSIDDITTTEIDDAFSVEHLADGRVRIGVHIAAPALGIQRGDEVDAIARTRLSTVY
MPGDKITMLPDSVVDAFTLAEGGLRPALSLYVIVNRETQEIVASETRAERVFVKNNLRHN
TLDELVTEEALAAGTGEYPHKEDIAVLWPFAQALFEKRQAARAGYGLRREVQRNTDFNFY
VEGEHITITPRRRGSPLDTIVAELAILANSSWGAFLHDHGVPGIYRTQRAFGAPTGPKRT
RMQTNAAPHEGLGVTQYAWSTSPLRRYVDLVNQWQLLACVQHGVTAKLAAPFKPKDADLF
AVVQGFDDTYTAYADHQRRMEYFWCLRWLKQENRKQVVASVVKGDLVRLEEIPLLLHVPG
LGVHARGTRLQMEVMSIDELTVEASVRLLHVLDAPTVTSGSEAEEADETDEGEEEEIVEA
SDESAESEAEAQAEADAEGDSNANDASGSEGSSNADAGQHITEPGR