Protein Info for ABIE53_003371 in Paraburkholderia graminis OAS925

Annotation: tRNA A37 threonylcarbamoyladenosine dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 283 transmembrane" amino acids 256 to 275 (20 residues), see Phobius details PF00899: ThiF" amino acids 31 to 276 (246 residues), 132.6 bits, see alignment E=6.3e-43

Best Hits

KEGG orthology group: None (inferred from 94% identity to bge:BC1002_2477)

Predicted SEED Role

"Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (283 amino acids)

>ABIE53_003371 tRNA A37 threonylcarbamoyladenosine dehydratase (Paraburkholderia graminis OAS925)
MSTTAQSDLTTSLDGHEAADRARRFGGIARLYGAPALAAFESAHVAVIGIGGVGSWVAEA
LARSAVGTLTLIDLDNVAESNTNRQIHALDGNYGKPKVEAMAERIAAINPSCDVRLVEDF
VEPDNFAATLGGGFDYVIDAIDSVRTKTALIAWCVERKQPLITIGGAGGQLDPTRIRIDD
LAATIQDPLLSKVRGQLRKQHGFQRGPKAKFKVSAVYSDEPLIYPEAAVCDIDAEAEHVA
TSPGYTGPVGLNCAGFGSSVCVTASFGFAAAAYVLRALAKQAV