Protein Info for ABIE53_003087 in Paraburkholderia graminis OAS925

Annotation: transcriptional regulator GlxA family with amidase domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 468 PF01965: DJ-1_PfpI" amino acids 147 to 301 (155 residues), 51.8 bits, see alignment E=1.3e-17 PF12833: HTH_18" amino acids 363 to 442 (80 residues), 72.1 bits, see alignment E=6e-24

Best Hits

Predicted SEED Role

"Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (468 amino acids)

>ABIE53_003087 transcriptional regulator GlxA family with amidase domain (Paraburkholderia graminis OAS925)
MSARHIVFAVAPDLVLLDACGPLEAFWRAELTMAAGRGDGRGAGAGTGNGTGSGSGSGSG
SGSGSGSGSGSGSGSGSGNGNGNGNGNGNGSGSGSGSGSGSGNGNGNGNGNGNGNGSGTG
NGNGNTNGNTNDASPVPHSPHSRPVAYRTTVASIDGGVLQTFPGLPVVTERLDSLDAQPI
DTLIVPGVPIDEHCTLQPELVAWIRRNAPRARRICSVCTGAFYLAAAGLLDGRRATTHWR
EAAHLARRFPNVHVDADPIFIRDAGSGARSHEHSSTTPRESVVWTSAGVTAGIDLALALI
DEDLGHAVAMQAARRLVVFMKRPGGQSQFSAALAAQASAGGPFDALHSWMAAHLRDDLTV
ERLAERARMTPRTFARRYVDEVGRTPAKTVSALRLEAASRALAESRRPLKRIALDCGFGS
EQNLRRAFVRRFGVLPLDYRERFMSAAAAPSSAASGVVAADSGRLETL