Protein Info for ABIE53_002892 in Paraburkholderia graminis OAS925

Annotation: alkylation response protein AidB-like acyl-CoA dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 380 PF02771: Acyl-CoA_dh_N" amino acids 6 to 107 (102 residues), 49.2 bits, see alignment E=1.3e-16 PF02770: Acyl-CoA_dh_M" amino acids 120 to 217 (98 residues), 63.5 bits, see alignment E=3.4e-21 PF00441: Acyl-CoA_dh_1" amino acids 229 to 356 (128 residues), 86.7 bits, see alignment E=3.8e-28 PF08028: Acyl-CoA_dh_2" amino acids 246 to 349 (104 residues), 29.3 bits, see alignment E=1.9e-10

Best Hits

KEGG orthology group: None (inferred from 88% identity to bug:BC1001_2405)

MetaCyc: 43% identical to pimeloyl-CoA dehydrogenase small subunit (Rhodopseudomonas palustris)
Pimeloyl-CoA dehydrogenase. [EC: 1.3.1.62]

Predicted SEED Role

"Acyl-CoA dehydrogenase family protein"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.3.1.62

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (380 amino acids)

>ABIE53_002892 alkylation response protein AidB-like acyl-CoA dehydrogenase (Paraburkholderia graminis OAS925)
MNFQHTEDRRMLADTLNRFISEQYGFATRDRIARSSHGFNSELWNRFGELGIIGALFDEA
SGGFGGGGFDIAVVFESLGRGLVVEPFLDTLIVGQAIARSGNDAQRALLGGLIDGSRIVA
LAHSEPDSHYELARVTTRAERNGDGDGSAWQLNGAKAVVQHGEQAAFFLVSARTEGADDS
EAGVTLFLVPRDAPGVSVRGYPKIDGGRAAEVSFENVILGDDALLGAAGNGFATLEYAIA
CGVLALCSEAVGAMDVAKDYTLDYLRTRQQFGVAIGSFQALQHRMADMLLEIEQARSAVI
NAAAALGAERKVRERAVSAAKYSIGRIGALVAQECIQLHGGIGMTWELPLAHYAKRLVMI
DHQLGDEDHHLERFVELGRE