Protein Info for ABIE53_002787 in Paraburkholderia graminis OAS925

Annotation: L-lactate dehydrogenase complex protein LldE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 240 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF02754: CCG" amino acids 3 to 84 (82 residues), 59.2 bits, see alignment E=1.8e-20 amino acids 132 to 215 (84 residues), 47.5 bits, see alignment E=8e-17

Best Hits

Swiss-Prot: 48% identical to LUTA_GEOKA: Lactate utilization protein A (lutA) from Geobacillus kaustophilus (strain HTA426)

KEGG orthology group: None (inferred from 97% identity to bug:BC1001_2298)

Predicted SEED Role

"Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE" in subsystem Lactate utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (240 amino acids)

>ABIE53_002787 L-lactate dehydrogenase complex protein LldE (Paraburkholderia graminis OAS925)
MRVGLFVTCLIDLMRPEIGFSVIKLLEGAGFEVVVPPAQTCCGQPAYNSGERRIARDLAE
KTLREFEQFDYVVVPSGSCGGMIRAHYGDLFADDPELMNRFGRLRARVFELTDFLVNVAK
VRLQPGEFAGQVTYHDSCSGLRELGVKAQPRELLAQVGVAVTEMKGCEHCCGFGGTFAVK
YGDISTAIVDEKCANIRDSGAGAVVLGDLGCMLNIEGRLRRTGDTATRVLHIAQVLAGDV