Protein Info for ABIE53_002507 in Paraburkholderia graminis OAS925

Annotation: [protein-PII] uridylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 859 TIGR01693: protein-P-II uridylyltransferase" amino acids 24 to 838 (815 residues), 806.6 bits, see alignment E=1.5e-246 PF01909: NTP_transf_2" amino acids 63 to 102 (40 residues), 26.2 bits, see alignment 2.2e-09 PF08335: GlnD_UR_UTase" amino acids 168 to 306 (139 residues), 150.5 bits, see alignment E=7.6e-48 PF01966: HD" amino acids 443 to 542 (100 residues), 34.5 bits, see alignment E=5.7e-12

Best Hits

Swiss-Prot: 84% identical to GLND_BURP0: Bifunctional uridylyltransferase/uridylyl-removing enzyme (glnD) from Burkholderia pseudomallei (strain 1106a)

KEGG orthology group: K00990, [protein-PII] uridylyltransferase [EC: 2.7.7.59] (inferred from 98% identity to bgf:BC1003_1286)

Predicted SEED Role

"[Protein-PII] uridylyltransferase (EC 2.7.7.59)" in subsystem Ammonia assimilation (EC 2.7.7.59)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.59

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (859 amino acids)

>ABIE53_002507 [protein-PII] uridylyltransferase (Paraburkholderia graminis OAS925)
MSSVPAVARSHATSLKADYKVAKAQLLERFRTATNVEGLMAALSRTTDDSLRAAWNTCEL
PAELALVAVGGFGRGELAPHSDIDILVLLPDAPLEHLEARIERFISLAWDLGLELGSSVR
SVSQCLEEAANDVTVRTSLLEARRITGSAALFDDFAKRYREALDPKAFFQAKVLEMRQRH
AKFQDTPYALEPNIKESPGGLRDLQLILWVTQAAGFGSSWRELEARGLITEREAQELRRN
EGFLKSLRARVHVTAGRRQDILVFDLQTPVAESFGYKPTATKRASEQLMRRYYWAAKAVT
QLATILIQNIEAQLFPSTSGITRVLSDRFVEKQGMLEIASDDLFQREPNAILEAFLLYEQ
TPGVKGLSARTLRAIYNAREVMDQHWRRDPENRRLFMDILKQPAGITHALRLMNQTSVLG
RYLLNFRRIVGQMQHDLYHVYTVDQHILMVLRNLRRFAVAEHAHEYPFCSQLIVSFDRPW
VLYVAALFHDIAKGRGGDHSTLGMADARRFCRNHGIEGDDGELVVWLVQQHLTMSQVAQK
QDTSDPEVIKRFAELVGTERRLTALYLLTVADIRGTSPKVWNTWKGKLLEDLYRATLAVL
GGARPDAHSELESRQEEALALLRLETVPEGAQKALWDKLDVGYFLRHDAADIAWQTRVLY
RYVETPTPIVRARPSPIGEALQVLVYVKDQPDLFAGICAYFDRNGLSVLDARVSTTRHGY
ALDNFLVAHTEEDVHYRDIANLVEQELTARLTGDGTWLPGPSKGRLSRLSRTFPVTPRVD
LRADDRGQYYILSVSANDRPGLLYSIARVLAEHRVGVASARINTLGERVEDVFLLDGHGL
SDNRLQIQVETELLRAIAV