Protein Info for ABIE51_RS16165 in Lysobacter sp. OAE881

Annotation: glycosyl hydrolase family 18 protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 698 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details PF17957: Big_7" amino acids 101 to 169 (69 residues), 73.7 bits, see alignment E=2.3e-24 PF00041: fn3" amino acids 201 to 273 (73 residues), 33.5 bits, see alignment E=6.6e-12 PF00704: Glyco_hydro_18" amino acids 298 to 683 (386 residues), 300.5 bits, see alignment E=3.4e-93

Best Hits

KEGG orthology group: K01183, chitinase [EC: 3.2.1.14] (inferred from 69% identity to smt:Smal_0542)

Predicted SEED Role

"Chitinase (EC 3.2.1.14)" in subsystem Chitin and N-acetylglucosamine utilization (EC 3.2.1.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.14

Use Curated BLAST to search for 3.2.1.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (698 amino acids)

>ABIE51_RS16165 glycosyl hydrolase family 18 protein (Lysobacter sp. OAE881)
MGGKLVRDANRSAARPVAFALSSLLALMGTIPAVQAQTVSCAAIPAWTASTIYNPGDKLV
YQNRLYQANIQIWNAPPTHCPTCGWYTDLGACGTGGQNQAPTVTLTSPANGATYNAGSSI
AVTANASDSDGTVASVEFFRGSVSLGVDTSAPYAVTWSNATAGSHSFTAKATDNQGATTT
SSAANITVNGTPPTDTTPPSVPTGLSATALSSSSIALSWNASTDNAGGAGVAGYDVYRGG
TLIASPTTTSYTNTGLTANTTYSYTVRARDAASPSNASAQSSAVSAKTLDGGTGGNKRVI
GYFAQWGIYARNYRVKNIDTSGSASKITHINYAFGNVRNNRCQVGVTIPTNESTGEGGDA
FADYTKAFQAGESVSGAADTWDQPLRGNWNQLKQLKAKYPNLKVLISLGGWTWSRGFASA
ARPENRVAFVSSCIDAYIRGNLPVTDGAGGAGAAAGVFDGIDLDWEYPSACGLTCGTPEE
SANFTALLAEFRRQLNAVRPGLLLTIAAGAGVDKVRVTDPAAYHQYLDYINVMTYDFHGT
WDARTNHHSALFDSPNDPSTGDQKLYNSNDAMEAFLTRGVPASKLNLGIGFYGRGWTGVA
NVNNGLYQSGSAAPGTYEAGNEDYKVLKDRPGTIYTDANARATWKYDGNTFWSYDTPAMV
TEKMSYVKAQNLGGAFFWEFSGDDAAGTLVNTINNGLK