Protein Info for ABIE51_RS15170 in Lysobacter sp. OAE881

Annotation: acyl-CoA dehydrogenase C-terminal domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 594 PF12418: AcylCoA_DH_N" amino acids 3 to 34 (32 residues), 38.2 bits, see alignment (E = 3.6e-13) PF02771: Acyl-CoA_dh_N" amino acids 43 to 158 (116 residues), 27.7 bits, see alignment E=8.9e-10 PF02770: Acyl-CoA_dh_M" amino acids 164 to 273 (110 residues), 52 bits, see alignment E=1.9e-17 PF00441: Acyl-CoA_dh_1" amino acids 284 to 451 (168 residues), 80 bits, see alignment E=6.3e-26 PF08028: Acyl-CoA_dh_2" amino acids 299 to 444 (146 residues), 29.1 bits, see alignment E=3.2e-10 PF12806: Acyl-CoA_dh_C" amino acids 468 to 584 (117 residues), 102.9 bits, see alignment E=4e-33

Best Hits

KEGG orthology group: None (inferred from 76% identity to sml:Smlt3352)

Predicted SEED Role

"Acyl-CoA dehydrogenase (EC 1.3.8.7)" (EC 1.3.8.7)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.3.8.7

Use Curated BLAST to search for 1.3.8.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (594 amino acids)

>ABIE51_RS15170 acyl-CoA dehydrogenase C-terminal domain-containing protein (Lysobacter sp. OAE881)
MSSYKAPLADMRFALFDVLDAEAQFQRLGFTDATRDVLDAVLDEAGRFTETVLAPLNPVG
DREGCKLDVSTGAVTTPSGFRQAYAQFVDGGWAGLTSPVEFGGQGLPQLVGVPLKEMIDA
ANLAWGNFPLLSHGAIEALLHHGETWQQEAFLKPLVEGRWTGTMCLTEPHCGSDLGLLKT
RAEPNGDGSYSITGTKIFITAGEHDFTDNIVHLVLARLPDAPAGSKGISLFVVPRERVAQ
DGSTGERNAVRCGSLEHKMGIHGSATCVMNFDGAQGYLVGAPHKGLMGMFTMMNSARLGV
GLQGLGLSERALQNALRYSRERLQMRALSGAKFPDKPADPIIVHPDVRRMLLTCKALIEG
GRLMGYDAAMQGDIAANSSDAAERELADAQAGFLTPIVKACLTEWGVECTYNALQCFGGH
GYIAEHGMEQLARDARITTLYEGTTGIQALDLLGRKILAMKGAGLKAFLARVHAFCEENA
GNESLAEFVGPLRETATRWQQLTMQIGQRAAGNADEIGAASFDYLMYSGYAVLAYWWARS
VATADASTHPQAFKDDKRATARFYFARILPRTLTHSAAIESGVAGLPELAVEAV