Protein Info for ABIE51_RS15085 in Lysobacter sp. OAE881

Annotation: serine hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 681 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details transmembrane" amino acids 535 to 559 (25 residues), see Phobius details amino acids 580 to 603 (24 residues), see Phobius details amino acids 615 to 641 (27 residues), see Phobius details amino acids 653 to 676 (24 residues), see Phobius details PF00144: Beta-lactamase" amino acids 83 to 398 (316 residues), 208 bits, see alignment E=1.1e-65

Best Hits

KEGG orthology group: None (inferred from 54% identity to pzu:PHZ_c2015)

Predicted SEED Role

"Beta-lactamase (EC 3.5.2.6)" in subsystem Beta-lactamase or Tn552 (EC 3.5.2.6)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.6

Use Curated BLAST to search for 3.5.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (681 amino acids)

>ABIE51_RS15085 serine hydrolase (Lysobacter sp. OAE881)
MKSPNRRGVSRPVAAALLSLAMSMSAIAAGPAGQAPVPPKAEPALPLPPGEATSVAVPVP
AAHERLTAADLEAWVDGFMPYALEQTDVAGSVVVVVKDGKVLFQKGYGYSDLVTRKPVDP
AQTLFRPGSVSKLFTWTAVMQLVEQGKLDLDKDINTYLDFKIPPYDGKPVTLRNVMTHTS
GMEEVIRGLIANNEKEIAPLDATLKHWIPERIYEPGSTPAYSNYATALAGYIVQRVSGEP
FEKYVANHIFAPLQMQHSSFSQPLEKNLQPMVSKGYKTASDGKPQPYEYINLAPAGSLAS
TGADMGNFMIAHLNNGAFGDARILGEATARQMHETGQESIKPLNRMMLGFYETSVNGHRA
IAHGGDTQWFHSDLQLFPDDNIGIYVSTNSAGKDGSARLIRDGLVTGFVNRYLPGPANVA
KGIDEATAKEHAQLMAGSYNSSRRADSNFMNLVYMLGQTKVVANEDGTISVPMLAGYSGA
PKKWREIAPFVWQDTGSGDRLAAEVVDGRVVRFSAEPIAAIMVFQRAAWWQTPGVFLTML
FGSLAALLFTVLAWPVSAMVRRHYGARYPLAGQDARAHRWVRIASLAVLVSVGAMIGMVF
AMMSDLSMMSPASDAYVIALRLLCTIVLPLGALIALWNAWVVLRSPRSWWAKLWSLVLAA
ACLSLLWIGFATHLIGFSANY