Protein Info for ABIE51_RS14800 in Lysobacter sp. OAE881

Annotation: formate dehydrogenase accessory sulfurtransferase FdhD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00129: formate dehydrogenase family accessory protein FdhD
  • amino acids 22 to 262 (241 residues), 205.5 bits, E=4.2e-65
• PF02634: FdhD-NarQ
  • amino acids 26 to 261 (236 residues), 245.4 bits, E=3.5e-77

Best Hits

Swiss-Prot: 56% identical to FDHD_XANOM: Sulfur carrier protein FdhD (fdhD) from Xanthomonas oryzae pv. oryzae (strain MAFF 311018)

KEGG orthology group: K02379, FdhD protein (inferred from 56% identity to xom:XOO_2631)

Predicted SEED Role

"Formate dehydrogenase chain D (EC 1.2.1.2)" in subsystem Formate hydrogenase (EC 1.2.1.2)

MetaCyc Pathways

• formate oxidation to CO₂ (1/1 steps found)
• oxalate degradation VI (1/4 steps found)
• purine nucleobases degradation II (anaerobic) (15/24 steps found)
• oxalate degradation III (1/5 steps found)
• superpathway of C1 compounds oxidation to CO₂ (4/12 steps found)
• purine nucleobases degradation I (anaerobic) (6/15 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Methane metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.2

Use Curated BLAST to search for 1.2.1.2

Protein Sequence (265 amino acids)

>ABIE51_RS14800 formate dehydrogenase accessory sulfurtransferase FdhD (Lysobacter sp. OAE881)
MNEPLQPVQALRLRAGDRAPHDDRVIVEAPIALLYNGESFAVMMATPDSLEDFALGFALG
EGIVGDASEFRLVDVVRHDEGVALHAAIPQPRFDALADRRRGMEGRSGCGLCGVESLQAA
LRPAPRVTSSMRVDVGSIRAALDALAAQQPLNALSGGVHAAGFAHGGGLLVREDVGRHNA
LDKLIGAMARNAIAPDSGFVVITSRASYEIVHKAATAGIGLVVAISAPTDLAIRTADAAG
VTLAAFARGDSLNVYAHPERIAAGS