Protein Info for ABIE51_RS14705 in Lysobacter sp. OAE881

Annotation: phosphodiesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1001 signal peptide" amino acids 1 to 42 (42 residues), see Phobius details transmembrane" amino acids 276 to 298 (23 residues), see Phobius details PF08447: PAS_3" amino acids 342 to 428 (87 residues), 61 bits, see alignment E=3.8e-20 TIGR00229: PAS domain S-box protein" amino acids 443 to 567 (125 residues), 63 bits, see alignment E=1.5e-21 PF00989: PAS" amino acids 448 to 547 (100 residues), 32.8 bits, see alignment E=2.2e-11 PF13426: PAS_9" amino acids 460 to 559 (100 residues), 31.2 bits, see alignment E=7.7e-11 PF00990: GGDEF" amino acids 596 to 716 (121 residues), 28.6 bits, see alignment E=4.1e-10 PF00563: EAL" amino acids 739 to 973 (235 residues), 214.7 bits, see alignment E=4.5e-67

Best Hits

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1001 amino acids)

>ABIE51_RS14705 phosphodiesterase (Lysobacter sp. OAE881)
MPPDERSRPASRRTQSAAAVLGFGLALAVVLAATLFAGAAADRANRLEAAERQNLALAAG
AERLVWLQLRNLERAMRGISNDVQGVAVAAPEHLPQLITEFFAGVSQRQQELESLELTDA
QGRPISSGRGEPDLPNWPDLRTPQPHPQSMFVGPLAQHRGQWLLPLALPMDDGRWIVARL
RTTELQKLVMHLDADRIHLIQLAGADGRLVADTRGEQYVGQPDDAVVPTRIEPTLMEEDD
DDQRDGVSRMTVSGLVPDYPLHVDVAIARGYILAPWWRLVAAGIALYLLYLCGLVYVVRV
VRRNARANAQMVERLTEAADNLRRAQQLGRTGTWIADRNGTICWSEPVSDLLGLPEGQSA
ATIGEFYAIVHPDDRERLSQHFNEAWRTGAPYSLDYRIIRGDDSRVRWISARGAATRDDD
GTVEMAGTVVDVTDRIEAQLALEEAERQFRLLFERNPLPFWVFDVRTLRFLEVNQAAIDQ
YGYSREEFLAMTIYDIRPEEHREEVANDLANHRPGDRDEIRLWVHRRKNGRLLEVRIHAT
DIDFRGNPARLVLAEDVTDRMAQQRELAYRASHDMTSGLLNADALAQRVDALPPGPCRIA
CVQLRGLELIEDSLGREAGHDTLRVIATRIARLGERFGVAGHVRGEEFALAVHPVEAWGE
ALECLQQELARPIPGEDTLHRLESWIGVSDMRTGDDEAVQAISNAGLAAHVARTEHRPIV
VFEPGMARHASDRLRLAGRIHRAIDAGEFELHFQILWDVAYSRPAGLETLIRWPQRGGGY
LPPSEFIGLCEDTGLIVPLGRWALREAAAAHRLLERAGFPGLPVAVNVSLMQFLDGDIAH
DIESVLREYELPRGALHIELTESVLMTRPEQALETLRRLQSAGVCLSLDDFGTGFSSMSY
LKQLPLDAIKIDQSFVRDVHRDERSASICQALLALGHGLGLAVVGEGVETRAQYEWLAMH
GCNQVQGFGIHRPAPLAQAIETLREMREWVDGPWQAFATEG