Protein Info for ABIE51_RS14330 in Lysobacter sp. OAE881

Annotation: phospholipase D family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13091: PLDc_2
  • amino acids 86 to 233 (148 residues), 43.7 bits, E=2.5e-15
  • amino acids 324 to 463 (140 residues), 71.7 bits, E=5.5e-24
• PF00614: PLDc
  • amino acids 418 to 442 (25 residues), 22 bits, see alignment (E = 1.3e-08)

Best Hits

KEGG orthology group: None (inferred from 58% identity to xca:xccb100_1455)

Predicted SEED Role

"Cardiolipin synthetase (EC 2.7.8.-)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 2.7.8.-)

MetaCyc Pathways

• cardiolipin and phosphatidylethanolamine biosynthesis (Xanthomonas) (3/4 steps found)
• cardiolipin biosynthesis II (2/3 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (8/13 steps found)

KEGG Metabolic Maps

• Aminophosphonate metabolism
• Glycerophospholipid metabolism
• High-mannose type N-glycan biosynthesis
• Nucleotide sugars metabolism
• Sphingolipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.8.-

Use Curated BLAST to search for 2.7.8.-

Protein Sequence (524 amino acids)

>ABIE51_RS14330 phospholipase D family protein (Lysobacter sp. OAE881)
MTRKLRWIGLAVFLLAAASLLSLYSYGRFAQRARGAPSQAIAATAVQTPLDRVIAPMEQA
HPGQAGLSLIADNLDAFTVRALTAREAGRSLDLQYYIWKPDLTGNLIVHEVLRAADRGVR
VRLLLDDLNSHKKDSVLAALDRHPNIEVRMFNPSRARQSYFLRGVEMVLRIFSLNRRMHN
KAWIADGRVAVVGGRNIGDEYFGAASESNFLDADLAVIGEPVRETSRIFDAYWNSSTAIP
LSELVDADELSLQRLRRVGVLEYRSKDAKPYIEQLRRSPSVQALLHGSREPRWTPNAHVY
SDPPEKAEGAPRRRNWLIDAITPAFTSAEREVFISSPYFVPGDDGVAGLLRMRDRGVRIG
ILTNSLAATDVAAVHGGYAPYRVPLLRGGIELYELKAQGPGGGRAGSGLLGSKSGEASLH
TKAFMVDGDCGFVGSVNFDPRSINLNTEMGILFTDRELTRDLMRLYAWKIGRENSYRLWL
ENGELRWEDAAAKPPRTWTEEPDADWKRRTMATVARWLPVESQL