Protein Info for ABIE51_RS13110 in Lysobacter sp. OAE881
Annotation: 2OG-Fe(II) oxygenase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Predicted SEED Role
"Similar to eukaryotic Peptidyl prolyl 4-hydroxylase, alpha subunit (EC 1.14.11.2)" in subsystem Proline, 4-hydroxyproline uptake and utilization (EC 1.14.11.2)
MetaCyc Pathways
- procollagen hydroxylation and glycosylation (1/6 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.14.11.2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (421 amino acids)
>ABIE51_RS13110 2OG-Fe(II) oxygenase (Lysobacter sp. OAE881) MNEDAVLLDLRRRAHDGSPQALYQLASALVARHELDEAFTLHRRAAEAGLANAQIEYARM LMYGVGCDAEPLRAAEWLLRAESVGSPIASYFLALMSLGGRTLPRDGRINERVLRAVRAD YPPALRAAAVHFGRKADPADQLRCLQLLERGAGLGDVIAARLFLERITRGEGDVPQPEAA ADLRGQLQAIGVGSLPEIVVPEFARSETAPGVLSMDDVLQPMDLHLQSTRPRVMTVDGLL SAEECRLLIANAEVHLTRSRTVDPDTGLPMEQEIRTSSDASFDAIQEDLALRCVQLRMAS AAGMPLDHAEHLVVLRYEPGQEYRPHRDYRPPSSIERDRPEAGNRMRTICAYLNTVEAGG QTEFPVAALRVEPRPGRAVVFENLHPDGSPDPDSLHAGLPVERGEKWLATLWLRQGRYRA F