Protein Info for ABIE51_RS09440 in Lysobacter sp. OAE881

Annotation: ribosome biogenesis GTPase Der

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 466 TIGR03594: ribosome-associated GTPase EngA" amino acids 3 to 434 (432 residues), 551.2 bits, see alignment E=2.9e-169 TIGR00231: small GTP-binding protein domain" amino acids 5 to 160 (156 residues), 75.4 bits, see alignment E=6.6e-25 amino acids 178 to 344 (167 residues), 86.7 bits, see alignment E=2.2e-28 PF02421: FeoB_N" amino acids 5 to 158 (154 residues), 49.7 bits, see alignment E=1.6e-16 amino acids 180 to 344 (165 residues), 49 bits, see alignment E=2.8e-16 PF01926: MMR_HSR1" amino acids 5 to 120 (116 residues), 101.4 bits, see alignment E=1.8e-32 amino acids 180 to 298 (119 residues), 93.3 bits, see alignment E=6.1e-30 PF00009: GTP_EFTU" amino acids 179 to 346 (168 residues), 49.6 bits, see alignment E=2e-16 PF14714: KH_dom-like" amino acids 356 to 434 (79 residues), 85.8 bits, see alignment E=1.1e-27

Best Hits

Swiss-Prot: 79% identical to DER_XANAC: GTPase Der (der) from Xanthomonas axonopodis pv. citri (strain 306)

KEGG orthology group: K03977, GTP-binding protein (inferred from 79% identity to xac:XAC2021)

Predicted SEED Role

"GTP-binding protein EngA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (466 amino acids)

>ABIE51_RS09440 ribosome biogenesis GTPase Der (Lysobacter sp. OAE881)
MLPLVALVGRPNVGKSTLFNALTRTRDALVHDQPGVTRDRNYGVARPEGKRPFAIVDTGG
IAGEDEGLAGATARQARSAAEEADLVLFVVDGREGASALDDDILAWLRKTARPAMLVVNK
TDGLDAQAAINEFARYGITDVIAVSSAHRQGIDELIDAVLKRVPEEGTATELDTDPSRIR
VAFIGRPNVGKSTLVNRLLGEERMIASEVPGTTRDSVSIDMERDGRLYRLVDTAGVRRKA
RVEEAVEKFSIVKTLQAIEQCQVAVVMLDASEGITDQDATVLGLALDAGRALVVAVNKWD
GLTDYQRQQAEALLTRKLGFVEWAEAVRISAKHGSGLRELFRAIHRAHASATHEFSTSEV
NKALEVAYETNPPPTVRGHVAKLRYAHPAANNPPTFVVHGTRLRTLSDTYKRYLENFFRK
RFKLVGTPVRFVFKEGANPYEGKKNVLTERQVAKKRRMIRHVKKGK