Protein Info for ABIE51_RS08935 in Lysobacter sp. OAE881
Annotation: penicillin-binding protein 1C
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K05367, penicillin-binding protein 1C [EC: 2.4.1.-] (inferred from 70% identity to xcv:XCV1168)Predicted SEED Role
"Penicillin-insensitive transglycosylase (EC 2.4.2.-) & transpeptidase PBP-1C" in subsystem Peptidoglycan Biosynthesis (EC 2.4.2.-)
KEGG Metabolic Maps
- Anthocyanin biosynthesis
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of plant hormones
- Carotenoid biosynthesis - General
- Flavone and flavonol biosynthesis
- Flavonoid biosynthesis
- Fructose and mannose metabolism
- Glycerolipid metabolism
- Glycosphingolipid biosynthesis - ganglio series
- Glycosphingolipid biosynthesis - globo series
- Glycosphingolipid biosynthesis - lacto and neolacto series
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
- High-mannose type N-glycan biosynthesis
- Keratan sulfate biosynthesis
- Lipopolysaccharide biosynthesis
- N-Glycan biosynthesis
- O-Glycan biosynthesis
- O-Mannosyl glycan biosynthesis
- Peptidoglycan biosynthesis
- Purine metabolism
- Sphingolipid metabolism
- Zeatin biosynthesis
Isozymes
Compare fitness of predicted isozymes for: 2.4.1.-, 2.4.2.-
Use Curated BLAST to search for 2.4.1.- or 2.4.2.-
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (783 amino acids)
>ABIE51_RS08935 penicillin-binding protein 1C (Lysobacter sp. OAE881) MKSLLAAQLLLIAAMLADLAFPLPLPDARDRGAVVTAADGTPLRAFADTGGIWRYAVEPE QVSPLYVQALLTYEDRWFWRHPGINPVAMLRAAGQWARSGRVVSGGSTLTMQVARILDSR QDARASNQRTPGRKLRQMLRALQLEVRLSKREILSLYVNHAPFGGTVEGVEAASWAYLGK PSSRLSHAEAALLAVLPQSPSRLRPDREPERARVARDKVLARMQQMQVWTPAQVTDARVE PVVARSLQPPRYAPLLAQRLRFEQPDAVRIASTLDLDLQRTLEDRVAAYFSQLPERTSAA LLVVDNATLEARAYVGSLAFADAARVGHVDMVKAWRSPGSTLKPFLYGLALDDGLIHSES LLVDAPQAFGDYRPGNFDAAFNGPVGAAQALRLSLNVPAVDLLDRVGPSRFSARLAHAGI RLQWPPGATPNLSMILGGTGARLEDLVGAYAALNRDGVAGRVRYTRDAPRVDRRLLSPGA AWIVREMLEANPRPGSAADTFDPRGRPRVAWKTGTSFGFRDAWALGGTRRYTVGVWVGRP DGTPLPGQYGAITALPLMFEVIDSLPRQRADAAPRPPPASVGTLDICWPLGLPLDPEAPQ LCRQRREAWTLDGSVPPTFAERDARLWSAGVERFDVDARTGLRLSADCSATHVRESREIA RWPALASPWLSSAARAAARLPRLSPDCVADGRDAVQELRIEGLNDRATLAPAPGGAQAVR LSLRALGGDARVRWLLDGRLIGESVGEGAFVHDFEQPGEHTLTALADSGAWSRLGFRLQA GSE