Protein Info for ABIE51_RS08320 in Lysobacter sp. OAE881
Annotation: NADH-quinone oxidoreductase subunit C
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 68% identical to NUOC_STRMK: NADH-quinone oxidoreductase subunit C (nuoC) from Stenotrophomonas maltophilia (strain K279a)
KEGG orthology group: K00332, NADH dehydrogenase I subunit C [EC: 1.6.5.3] (inferred from 68% identity to psu:Psesu_1843)Predicted SEED Role
"NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.6.5.3
Use Curated BLAST to search for 1.6.5.3
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (247 amino acids)
>ABIE51_RS08320 NADH-quinone oxidoreductase subunit C (Lysobacter sp. OAE881) MAQPYDFMDAQALSGRLTARFPEAMVVIAPGRNEVTIDVAAPQWLATAIALRDEFGFELC VDVSGVDYLSYGSDEWDTDVSSEGFSRGVEGKSAGRFVWGEQPNGAAAAPERRFAAVAHL LSCQHNERVRLRTFADNDDLPVVDSLTSVWPGVNWFEREAFDLYGIVFEGHPDLRRILTD YGFVGHPFRKDFPLIGNVEVRYDADKKRVVYEPVSIEPRVLVPRVIRDDARYETAQGEAA QRGEVKK