Protein Info for ABIE51_RS07475 in Lysobacter sp. OAE881

Annotation: ribonuclease R

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 827 TIGR02063: ribonuclease R" amino acids 98 to 806 (709 residues), 871.7 bits, see alignment E=4e-266 PF08461: HTH_12" amino acids 101 to 151 (51 residues), 21.5 bits, see alignment 4.7e-08 TIGR00358: VacB and RNase II family 3'-5' exoribonucleases" amino acids 159 to 805 (647 residues), 725.4 bits, see alignment E=6e-222 PF08206: OB_RNB" amino acids 166 to 224 (59 residues), 84.1 bits, see alignment 1.1e-27 PF17876: CSD2" amino acids 244 to 321 (78 residues), 76.1 bits, see alignment E=4.7e-25 PF00773: RNB" amino acids 343 to 675 (333 residues), 368.9 bits, see alignment E=6.5e-114 PF00575: S1" amino acids 723 to 802 (80 residues), 39.1 bits, see alignment E=2e-13

Best Hits

KEGG orthology group: K12573, ribonuclease R [EC: 3.1.-.-] (inferred from 75% identity to psu:Psesu_0923)

Predicted SEED Role

"3'-to-5' exoribonuclease RNase R" in subsystem RNA processing and degradation, bacterial

Isozymes

Compare fitness of predicted isozymes for: 3.1.-.-

Use Curated BLAST to search for 3.1.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (827 amino acids)

>ABIE51_RS07475 ribonuclease R (Lysobacter sp. OAE881)
MKKKASGSSKSGSKSGSPKSGPRSGKNASGKPGAGKAQSAKSGKFAGASGGGRKAPLARP
GWMPEPLPPAQRGRGGAGSGFHDPYAAREAARYEQPIASREMILQLLAQADGPLSADEIA
QRLSLTEESRFDALGKRLAAMVRDGQLLRNRMGEFLPAQQLDLIPGVVIANPDGFGFLRP
ESGGGDDLFLPPMEMRKAMHGDRVLARVTGVDRRGRREGAILRVLERRLNRLIGRFCLEA
GISYVVPDDRRIQRNVQVPPDERMNAQNGQLVVVELIESPDEHGPQRTPIGRVLAVLGDR
LTASLAVQAAIHGHEIPHEFPQAVLDEASDVPLTVPEEIAAERVDLRELPLVTIDGEDAK
DFDDAVYCEPNRNGFRLVVAIADVSHYVRPGTPLDDEAQKRATSVYFPGFVVPMLPETLS
NGICSLNPKVDRLCFVCDMQIDREGEVTRSKFFEAVMNSHARLTYTQVWNAVGEDVREED
RQDAIERIGSLLPNVQRLHQLYQILAKARERRGAIEFESSEVRFVLGPKGEVVQAGMLQR
NDAHKLIEECMIAANVEAAKYLMASHVPSPFRIHERPPEQKYADLLEFLKEFKLRMPPWN
RVEPRDFTALLKKIRERPDAALIESVLLRSQSLAVYSPENVGHFGLALEAYTHFTSPIRR
YPDLLVHRAIKYALTGGRPEKYRYSPSEMAALTLQCSERERRADEAEREVDERYRAAWME
QHVGGEFDGVISGVTSFGLFVELVESKVTGMVHVTQLPHDYYQFDPIRKTLSGERAGRQF
RLGDRVRIVVMKASVEDRKIDFKLVEDRGMKPLPPRGQPAKRVKQKY