Protein Info for ABIE51_RS06620 in Lysobacter sp. OAE881

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 375 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF00561: Abhydrolase_1" amino acids 77 to 351 (275 residues), 68.5 bits, see alignment E=1.4e-22 PF12697: Abhydrolase_6" amino acids 79 to 355 (277 residues), 66.6 bits, see alignment E=1.1e-21 PF12146: Hydrolase_4" amino acids 105 to 349 (245 residues), 59.9 bits, see alignment E=5e-20 PF00326: Peptidase_S9" amino acids 137 to 224 (88 residues), 22.7 bits, see alignment E=1.3e-08

Best Hits

KEGG orthology group: None (inferred from 66% identity to psu:Psesu_3029)

Predicted SEED Role

"Proline iminopeptidase (EC 3.4.11.5)" in subsystem Proline, 4-hydroxyproline uptake and utilization (EC 3.4.11.5)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.5

Use Curated BLAST to search for 3.4.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (375 amino acids)

>ABIE51_RS06620 alpha/beta hydrolase (Lysobacter sp. OAE881)
MRKVVFARLFAAFAMVASAFAANAQACKDTAAYEPARKIIADLGRIETPNGVQESYKTRI
NGIDQWVNVRGQDRDNPIVLFVHGGPASPLTPTLWQFQRPLEEYFTMVTYDQRGAGKTFV
ANDEAKVAGTIHIPNFVDDVVAMAEDVRARYGKRKLILMGHSWGTIIAMQAALKRPDLFH
AYIGVGQVINVRENERISFDYAMATAKAKGNAEAVREMEAIAPYPGNTPITRERIIAARK
WAQYYGGLTAYRDESTYFYRAPLLSPEYTDAERCAVDAGNVFTLGRILPEFLAVDMSGVR
EFPIPVLMFMGRHDYTTPSEPTDAWLKQVKAPYKQGVWFEHASHMVPWEEPGKLLVSLVQ
YVRPLADDTPGVTKK