Protein Info for ABIE51_RS05825 in Lysobacter sp. OAE881

Annotation: elongation factor G

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 706 TIGR00484: translation elongation factor G" amino acids 1 to 704 (704 residues), 1180.6 bits, see alignment E=0 PF00009: GTP_EFTU" amino acids 9 to 288 (280 residues), 211.7 bits, see alignment E=1.8e-66 TIGR00231: small GTP-binding protein domain" amino acids 10 to 186 (177 residues), 109.8 bits, see alignment E=1.2e-35 PF03144: GTP_EFTU_D2" amino acids 329 to 396 (68 residues), 71.6 bits, see alignment E=1.4e-23 PF14492: EFG_III" amino acids 409 to 483 (75 residues), 117.9 bits, see alignment E=4.1e-38 PF03764: EFG_IV" amino acids 484 to 612 (129 residues), 147 bits, see alignment E=5.7e-47 PF00679: EFG_C" amino acids 614 to 699 (86 residues), 97.7 bits, see alignment E=8.3e-32

Best Hits

Swiss-Prot: 90% identical to EFG_XANCP: Elongation factor G (fusA) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K02355, elongation factor G (inferred from 90% identity to xcc:XCC0892)

Predicted SEED Role

"Translation elongation factor G" in subsystem Translation elongation factor G family or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (706 amino acids)

>ABIE51_RS05825 elongation factor G (Lysobacter sp. OAE881)
MARTTPIERYRNFGIMAHIDAGKTTTSERILFYTGVSHKIGEVHEGAATMDWMEQEQERG
ITITSAATTAFWKGMDKSLPEHRFNIIDTPGHVDFTIEVERSLRVLDGAVFVLCAVGGVQ
PQSETVWRQANKYSVPRMAFVNKMDRTGANFDKVVEQLKARLGAYAVPMQVPIGAEDGFE
GVIDLLKMKAIHWDVASQGTKFEYRDIPAELQAKSEAARSFMVEAAAEANEALMDKYLSE
GELTEAEIIAGLRERTLRVEIVPVFCGSAFKNKGVQAMLDGVINLLPSPADRPPVQGIDE
NEKEDSRKASDSEPFSALAFKIMTDPFVGALTFFRVYSGVLNSGDQVFNPVKSKKERIGR
ILQMHANQRDEIKEVRAGDIAAAVGLKDVTTGDTLCSGDHIITLERMTFPEPVISMAVEP
KTKSDQEKMGMALSRLAQEDPSFRVRTDEESGQTIIAGMGELHLDIIVDRMRREFNVEAN
VGKPQVAYRETIRKSDVKSDYKHAKQSGGKGQYGHVVIELSPMTEADRANPDVENDFLFV
NDITGGVIPKEFIPAVEKGLRETITSGPLAGFPVVNVKVKLVFGSYHDVDSSEMAFKLAS
SMAFKEGFRKADPVLLEPMMKVEIVTPEDYVGDVMGDVSRRRGLLSGQDDSPSGKVINAM
VPLGEMFGYATSLRSMSQGRATFTMEFDHYAEAPTNIADAVMKKGG