Protein Info for ABIE51_RS04445 in Lysobacter sp. OAE881

Annotation: CDP-diacylglycerol--serine O-phosphatidyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 transmembrane" amino acids 15 to 35 (21 residues), see Phobius details amino acids 41 to 58 (18 residues), see Phobius details amino acids 79 to 98 (20 residues), see Phobius details amino acids 110 to 128 (19 residues), see Phobius details amino acids 141 to 159 (19 residues), see Phobius details amino acids 171 to 193 (23 residues), see Phobius details amino acids 205 to 222 (18 residues), see Phobius details amino acids 228 to 245 (18 residues), see Phobius details PF01066: CDP-OH_P_transf" amino acids 17 to 177 (161 residues), 72.8 bits, see alignment E=2.2e-24 TIGR00473: CDP-diacylglycerol-serine O-phosphatidyltransferase" amino acids 25 to 192 (168 residues), 116.5 bits, see alignment E=5.9e-38

Best Hits

KEGG orthology group: K00998, phosphatidylserine synthase [EC: 2.7.8.8] (inferred from 69% identity to xca:xccb100_3714)

Predicted SEED Role

"CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 2.7.8.8)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.8.8

Use Curated BLAST to search for 2.7.8.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (258 amino acids)

>ABIE51_RS04445 CDP-diacylglycerol--serine O-phosphatidyltransferase (Lysobacter sp. OAE881)
MDETQSTPRPRNRGIYLLPNLFTTGGLFAGFYAIIAATQGRFDDACIAVFVAGILDGLDG
RVARLTNTQSEFGVQYDSLADLVSFGLAPALVMYHWALQEMRLDGPIPGKIGWVAAFVYA
ACAALRLARFNSQVGTVDKRWFIGLASPAAAGLVASFVWTCHDLGYTGEQLRYFALGVTV
TAGLLMVSRLRYFSFKGGGPRHDRVPFLAIVVVLAVLVGIAIDPPRVLLAIGALYALSGP
AYAAFRRVRRAPVSEAAP