Protein Info for ABIE51_RS04255 in Lysobacter sp. OAE881

Annotation: PilT/PilU family type 4a pilus ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 370 TIGR01420: twitching motility protein" amino acids 6 to 342 (337 residues), 438.9 bits, see alignment E=7.1e-136 PF00437: T2SSE" amino acids 46 to 269 (224 residues), 129 bits, see alignment E=9.8e-42

Best Hits

Swiss-Prot: 42% identical to PILT_PSEAE: Twitching mobility protein (pilT) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K02670, twitching motility protein PilU (inferred from 88% identity to psu:Psesu_2467)

Predicted SEED Role

"Type II secretion system protein-like protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (370 amino acids)

>ABIE51_RS04255 PilT/PilU family type 4a pilus ATPase (Lysobacter sp. OAE881)
MDIGYFLKLMTEKNASDMFLTTGAPVYIKVEGKLYPLGNTGLPPGMVKKIAYSLMDEGQV
PLFERDLELNMALALPEAGRFRINVFKQRGEVGMVIRAIRSVIPSIEELQLPQVLKDIIM
APRGLVLIVGSTGSGKSTTLASMIDYRNSNISGHILTIEDPIEYLHKHKKSIVNQREVGL
DTHAFHNALKNAMREAPDVILIGEILDATTMEAAIAFAETGHLCLATLHSNNADQTLERI
LNFFPEAAHKNVLMNLALNLRAVVSQRLVVGTDGRRVPAAEVLINTPHIRDLMRRGQVHE
IKQAMEESLEEGMESFDQCLFRLYKEGRIDMEEALKAADSREGLSLKFRLSEGSSGEHDP
YAEIYDTATQ