Protein Info for ABIE51_RS03615 in Lysobacter sp. OAE881

Annotation: xylose isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 80% identical to XYLA2_XANC8: Xylose isomerase 2 (xylA2) from Xanthomonas campestris pv. campestris (strain 8004)

KEGG orthology group: K01805, xylose isomerase [EC: 5.3.1.5] (inferred from 86% identity to psu:Psesu_2930)

MetaCyc: 51% identical to xylA (Weizmannia coagulans 36D1)
Xylose isomerase. [EC: 5.3.1.5]

Predicted SEED Role

"Xylose isomerase (EC 5.3.1.5)" in subsystem Xylose utilization (EC 5.3.1.5)

MetaCyc Pathways

superpathway of glucose and xylose degradation (16/17 steps found)
D-xylose degradation I (2/2 steps found)
superpathway of pentose and pentitol degradation (8/42 steps found)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (443 amino acids)

>ABIE51_RS03615 xylose isomerase (Lysobacter sp. OAE881)
MSNHFIGAKEYFPGIGRIPFEGRDSDNPLAFKVYDAKKKIGGKTMEEHLKFAVCYWHTFT
NAGHDPFGPGTRKFPWEGATPMQTAENKVDAAFEFITKLGVPYYCFHDVDLAPDAEDIGE
YEKNLKHMVALAKQRQNDTGVKLLWGTANLFSHPRYMNGASTNPDFNVVARAAVQVKAAL
DATVELGGEHYVFWGGREGYASLVNTNMKREVEHFARFLTMARDYGRSIGFKGYYLIEPK
PMEPMKHQYDFDSATVAGFLREHGLHKDFKLNIEANHATLSGHTFEHDLQVASDHDLLGS
IDANRGNAQNGWDTDQFPTDLYDTVGAMMVVLRQGGLVGGLNFDAKARRESTDMEDLFIA
HVGGMDAFARGLEVAHALLNDSPWETWRKERYASFDGGAGQDFERGKLGLADLRELALKN
GEPRQISGKQERYENLLNQYLLR