Protein Info for ABIE51_RS02185 in Lysobacter sp. OAE881

Annotation: SDR family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF00106: adh_short" amino acids 12 to 202 (191 residues), 169.9 bits, see alignment E=9.2e-54 PF01370: Epimerase" amino acids 13 to 178 (166 residues), 27.8 bits, see alignment E=3.3e-10 PF08659: KR" amino acids 14 to 173 (160 residues), 43.4 bits, see alignment E=7.3e-15 PF13561: adh_short_C2" amino acids 20 to 253 (234 residues), 205.1 bits, see alignment E=2.6e-64

Best Hits

KEGG orthology group: K08081, tropine dehydrogenase [EC: 1.1.1.206] (inferred from 75% identity to xcv:XCV3936)

Predicted SEED Role

"Short-chain dehydrogenase/reductase SDR"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.206

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (258 amino acids)

>ABIE51_RS02185 SDR family oxidoreductase (Lysobacter sp. OAE881)
MDPKRWRLDGQLALVTGGSAGIGRAVARELLGFGADVLLAARDVAGLDAVRAELMEDFPE
RDVQAFVADVADDEQRRELLDWVEDFGEGLHILVNNAGGNLTKAATDYTEDEWRQVFEVN
VFSAFELSRYAHPLLTKHASSSIVNVGSVSGTTHVRTGAPYGMSKAAMHQMTRNLAVEWA
EDGVRVNAVAPWYIRTRRTSDKLADPDYLDEVLLRTPLGRIGEPEEVAAAIAFLCLPAAG
YITGECIAVDGGFLRYGF