Protein Info for ABIE51_RS01325 in Lysobacter sp. OAE881

Annotation: TCR/Tet family MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 422 transmembrane" amino acids 15 to 38 (24 residues), see Phobius details amino acids 52 to 73 (22 residues), see Phobius details amino acids 85 to 104 (20 residues), see Phobius details amino acids 110 to 132 (23 residues), see Phobius details amino acids 144 to 166 (23 residues), see Phobius details amino acids 172 to 192 (21 residues), see Phobius details amino acids 225 to 248 (24 residues), see Phobius details amino acids 262 to 280 (19 residues), see Phobius details amino acids 292 to 310 (19 residues), see Phobius details amino acids 316 to 337 (22 residues), see Phobius details amino acids 351 to 376 (26 residues), see Phobius details amino acids 387 to 406 (20 residues), see Phobius details PF06779: MFS_4" amino acids 16 to 168 (153 residues), 27.8 bits, see alignment E=2.6e-10 PF07690: MFS_1" amino acids 19 to 365 (347 residues), 167.5 bits, see alignment E=6e-53 PF00083: Sugar_tr" amino acids 53 to 195 (143 residues), 46.6 bits, see alignment E=3.6e-16

Best Hits

KEGG orthology group: K08151, MFS transporter, DHA1 family, tetracycline resistance protein (inferred from 72% identity to psu:Psesu_3021)

Predicted SEED Role

"Tetracycline-efflux transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (422 amino acids)

>ABIE51_RS01325 TCR/Tet family MFS transporter (Lysobacter sp. OAE881)
MTDTAPATGARRRAALVFIFITILIDVLSFGLIIPVLPHLIEQFAGGDTAHAAYWVAAFG
FLFAGIQFVTSPIQGALSDRFGRRPVILLSCLGLGLDFVFMALAPSLTWLLVGRIISGIT
SASFTTANAYVADVTPPDKRAKSYGLLGAAFGVGFIVGPLIGGALGEVDLRLPFWFAAGL
ALLNFCYGLFVLPESLPPERRSPRFDWSHANPIGSLGLLKRYPQVFGLAAVVFIANLAHY
VYPSVFVLFADYQYQWGPREVSYVLAIVGVLNVIVQAGLVGKAVHALGERRALMLGLACG
AIGFGIYGFAHVGWMFLVGLPISAIWGLAAPSTQALITRQVGPEVQGRIQGALMSLVSLA
GIIGPVVFAGSFGYFIDDRAPMHLPGAPFLIAGILLAVAVGIAWRYARVPATTPAASVVE
PG