Protein Info for ABIE51_RS01085 in Lysobacter sp. OAE881

Annotation: HAD family hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01488: HAD phosphoserine phosphatase-like hydrolase, family IB
  • amino acids 3 to 185 (183 residues), 86.7 bits, E=1.9e-28
• TIGR01490: HAD hydrolase, family IB
  • amino acids 3 to 191 (189 residues), 119.6 bits, E=2.1e-38
• PF12710: HAD
  • amino acids 4 to 183 (180 residues), 124.2 bits, E=4.5e-40

Best Hits

KEGG orthology group: None (inferred from 57% identity to sec:SC054)

Predicted SEED Role

"Phosphoserine phosphatase (EC 3.1.3.3)" in subsystem Glycine and Serine Utilization or Serine Biosynthesis (EC 3.1.3.3)

MetaCyc Pathways

• superpathway of sulfate assimilation and cysteine biosynthesis (9/9 steps found)
• superpathway of L-serine and glycine biosynthesis I (4/4 steps found)
• L-serine biosynthesis I (3/3 steps found)

KEGG Metabolic Maps

• Glycine, serine and threonine metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.3

Use Curated BLAST to search for 3.1.3.3

Protein Sequence (197 amino acids)

>ABIE51_RS01085 HAD family hydrolase (Lysobacter sp. OAE881)
MNLALFDFDGTITTRELMPDFVRMATTKRRLMVGRVVLAPIFIGYKAGVVSGNAIRDRIA
DFAFRGLPQRDLQAAGEHFARDVIPPTVRPEAMERLQWHRDQGDTIVVVSGSFDLYLSHW
CALHGLELLCSSLEVRDGVMTGRFEGAQCVGAEKARRVREHYDLSRFPVVYAYGDTHEDR
DLLALAHRRWYRGREVE