Protein Info for ABCV34_RS12260 in Castellaniella sp019104865 MT123

Annotation: TRAP transporter large permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 53 to 72 (20 residues), see Phobius details amino acids 84 to 106 (23 residues), see Phobius details amino acids 111 to 130 (20 residues), see Phobius details amino acids 142 to 160 (19 residues), see Phobius details amino acids 169 to 191 (23 residues), see Phobius details amino acids 215 to 233 (19 residues), see Phobius details amino acids 239 to 258 (20 residues), see Phobius details amino acids 270 to 291 (22 residues), see Phobius details amino acids 303 to 326 (24 residues), see Phobius details amino acids 332 to 351 (20 residues), see Phobius details amino acids 357 to 383 (27 residues), see Phobius details amino acids 395 to 415 (21 residues), see Phobius details PF06808: DctM" amino acids 6 to 414 (409 residues), 412.8 bits, see alignment E=7.6e-128 TIGR00786: TRAP transporter, DctM subunit" amino acids 17 to 419 (403 residues), 449.1 bits, see alignment E=6.3e-139

Best Hits

Swiss-Prot: 39% identical to YIAN_ECOLI: 2,3-diketo-L-gulonate TRAP transporter large permease protein YiaN (yiaN) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 81% identity to put:PT7_3020)

MetaCyc: 39% identical to 2,3-diketo-L-gulonate:Na+ symporter - membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-235

Predicted SEED Role

"TRAP-type transport system, large permease component, predicted N-acetylneuraminate transporter" in subsystem Sialic Acid Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (425 amino acids)

>ABCV34_RS12260 TRAP transporter large permease (Castellaniella sp019104865 MT123)
MSQLMVVSMLLFFGLTVPVAVSIGLATMVGVGFDGHMTWLVIAQQLYAALDKYPLMAVPF
FILAGNLMEAGGISERMVEFAKSVVGGVQGGLACSCVLTCMIFAAVAGSSVATTFAVGSI
LIPAMVKHGYPAPFAASLQASAAELGVIIPPSIPMILFAVSTDTSVGEVFISGIGPGILI
VVGLMLYVWLYARRNGLGTHDGDGRLPVWAAFRKAWWALLMPVIILGGIYGGIFTPTEAS
AVAVVYALFVGVFIYRRLNWAILGRTFHSSVMSTAIIMFIIANAGVFGFLLNRAGVPMAL
GEWLSHLFGSEVTFLLGVNVALFIIGMFIETSASIVVLAPLLLPVATQFGVDPAHFGVIM
VVNLALGMVTPPFGVNLFAACTVAKVPIERLIRPLLPFVGVVLTCLMVITYWPGLSLFFR
DLVYR