Protein Info for ABCV34_RS10855 in Castellaniella sp019104865 MT123

Annotation: penicillin-binding protein 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 686 transmembrane" amino acids 19 to 39 (21 residues), see Phobius details TIGR03423: penicillin-binding protein 2" amino acids 18 to 613 (596 residues), 716.4 bits, see alignment E=1.4e-219 PF03717: PBP_dimer" amino acids 61 to 238 (178 residues), 144 bits, see alignment E=7.1e-46 PF00905: Transpeptidase" amino acids 270 to 608 (339 residues), 203.8 bits, see alignment E=3.6e-64

Best Hits

KEGG orthology group: K05515, penicillin-binding protein 2 (inferred from 72% identity to put:PT7_2391)

Predicted SEED Role

"Penicillin-binding protein 2 (PBP-2)" in subsystem Peptidoglycan Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (686 amino acids)

>ABCV34_RS10855 penicillin-binding protein 2 (Castellaniella sp019104865 MT123)
MFEFRKTGLRQRQTVLLRAWVAGLFALVCLLLLAGRLWYLQVIRYDNLSARAEQNRITIV
PIPPQRGQITDRHGQVLATNQRDYTLLVTRAQVKGKLEDLLNRLRELVYISDSDQRKFLR
LYQQSGRYAPVLLRNNLSDIEASWFAVHAFEFPGVSLQARWVRSYPEHESAAHVLGFVGR
ISEADQQHLEETSQEGNYRGTLVMGKKGIEKTWEKALHGRTGVEELEVTATGRPVRELSR
TDPIPGSNLELSLDEGLEKLAEAQFAGRRGALVAIAPHTGEVLAFVSSPSFDPNLFVDGI
DVENWRKLNDSPDHPLINRPLYGTYPIGSTYKPFVALAALEMGLRGPQDLIPDPGYFELA
GQKFRNAGGAAYGPTNMHKAIMVSSDTYFFSLGALMDVDALHDFSKQFGFGQITGIDLDG
ERRGVLPSREWKRKAYKKPAQQHWFRGETVSVTVGQGYNAFTLLQLAQATAVLANDGVYM
KPHLVRRIINPVTGHFTYPVVGPQYTIPLKPAYLKVVQDAMVDVIRKGTARRAFEGATYQ
AAGKTGTAQVYSLRGAKYKAHAVDERLRDHALFMAYAPVDDPQIAVALIVENGGWGASVA
APIARAVFDYWLDPAQVAERRRQLRTEQESRKVVDAVTSSGTGAGTGPLQPVPDAAPAPD
EEGTPEPAPLPDAETPPEDGAQEDSP