Protein Info for ABCV34_RS09970 in Castellaniella sp019104865 MT123

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 356 transmembrane" amino acids 84 to 102 (19 residues), see Phobius details PF00005: ABC_tran" amino acids 20 to 161 (142 residues), 123.4 bits, see alignment E=1.1e-39 PF08402: TOBE_2" amino acids 272 to 350 (79 residues), 48.9 bits, see alignment E=5.9e-17

Best Hits

Swiss-Prot: 46% identical to POTA_PSEF5: Spermidine/putrescine import ATP-binding protein PotA (potA) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)

KEGG orthology group: K02052, putative spermidine/putrescine transport system ATP-binding protein (inferred from 65% identity to xau:Xaut_0860)

MetaCyc: 40% identical to ABC-type 3-(6-sulfo-alpha-D-quinovosyl)-sn-glycerol transporter ATP-binding subunit (Agrobacterium fabrum)
7.5.2.M1 [EC: 7.5.2.M1]

Predicted SEED Role

"Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1)" in subsystem Polyamine Metabolism (TC 3.A.1.11.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.M1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (356 amino acids)

>ABCV34_RS09970 ABC transporter ATP-binding protein (Castellaniella sp019104865 MT123)
MSDVILQALSKQFGNSTAVDHISLNIRSGELVTLLGPSGCGKTTTLRMLGGFIRPTSGQI
LVGGRNVTDLPPNLRNMGFGFQNYALFPHMTVAANVAFGLEMRRVRKDEIRKKVNAALDR
VRLREFAERMPKALSGGQQQRVALARALVIEPDVLLLDEPLSNLDANLRQGLKNEIREIQ
RSMGITTVFVTHDQDEALSVSDRVVVMRNGRVEQSGSPDEIFDTPASQFVAEFMGVTNIL
HGRVESPGAFRVDSGDLVPAASAGDDGKVVMALRPERIQIGDAQDAAGGGALKAKIRLVT
YRGLVIDYQVRTESGMVLTARRQAPVIGGPTVLPQGQDVRLSWHSDAGVLVPASGA