Protein Info for ABCV34_RS09785 in Castellaniella sp019104865 MT123

Annotation: peptide-methionine (S)-S-oxide reductase MsrA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 175 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details TIGR00401: peptide-methionine (S)-S-oxide reductase" amino acids 2 to 153 (152 residues), 176.5 bits, see alignment E=2.3e-56 PF01625: PMSR" amino acids 3 to 154 (152 residues), 208.2 bits, see alignment E=3.8e-66

Best Hits

Swiss-Prot: 58% identical to MSRA_CHRVO: Peptide methionine sulfoxide reductase MsrA (msrA) from Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)

KEGG orthology group: K07304, peptide-methionine (S)-S-oxide reductase [EC: 1.8.4.11] (inferred from 62% identity to bpe:BP3041)

Predicted SEED Role

"Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)" (EC 1.8.4.11)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.4.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (175 amino acids)

>ABCV34_RS09785 peptide-methionine (S)-S-oxide reductase MsrA (Castellaniella sp019104865 MT123)
MEQAIFGGGCFWCLEPVFRALAGVCDVQPGYCGGHVDAPTYEQVCAHDTGHVEVVRIDYD
PQQVSYRTLLEVFFGTHDPTTPDRQGHDIGPQYASVIFYQDDAQRLAAQAVRDEVQAHFD
SPICTRIQPAGTFWPAEPLHREYYRQHPEQGYCQFVIAPKMAKFRQKYANLLGRA