Protein Info for ABCV34_RS01525 in Castellaniella sp019104865 MT123

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 transmembrane" amino acids 21 to 47 (27 residues), see Phobius details amino acids 55 to 77 (23 residues), see Phobius details amino acids 89 to 107 (19 residues), see Phobius details amino acids 113 to 137 (25 residues), see Phobius details amino acids 158 to 179 (22 residues), see Phobius details amino acids 189 to 208 (20 residues), see Phobius details amino acids 246 to 267 (22 residues), see Phobius details amino acids 280 to 301 (22 residues), see Phobius details amino acids 308 to 328 (21 residues), see Phobius details amino acids 337 to 360 (24 residues), see Phobius details amino acids 373 to 394 (22 residues), see Phobius details amino acids 400 to 421 (22 residues), see Phobius details PF00083: Sugar_tr" amino acids 17 to 219 (203 residues), 92.4 bits, see alignment E=3.1e-30 amino acids 256 to 433 (178 residues), 47 bits, see alignment E=1.8e-16 PF07690: MFS_1" amino acids 24 to 372 (349 residues), 102.6 bits, see alignment E=2.3e-33 amino acids 287 to 427 (141 residues), 36.6 bits, see alignment E=2.5e-13

Best Hits

KEGG orthology group: K03762, MFS transporter, MHS family, proline/betaine transporter (inferred from 54% identity to pst:PSPTO_3801)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (449 amino acids)

>ABCV34_RS01525 MFS transporter (Castellaniella sp019104865 MT123)
MSQRTTHAAPDPALRKVTVAAIAGTVIEWFDFAIYGFMAPAIALAFFPEGNPVTALLQTF
AIFAVAFALRPIGGAFFGMMGDRIGRKRVLALTVLLMSCATAAIGLIPNHESIGIWAAVL
LTVARCVQGFSAGGEYAGAVTYVIEHAPDHQRSRYSSWMPSATFASFALAALISYFLAVG
LSTAEMNAWGWRVPFLVAAPLGLVAFYIRSHLRESPLFQKVLESSGVPHSSLGQTLAVQW
KSMLRLGGYISLTAVSFYIFSTYMTTFLRSVMHMPADRVLMSNVVALTFAAAIAPVIGPI
CDRVGRRATMFASVVLLGGLSVPAYILASSGTLGHALVAQLVLALGAVTANVVTAVLLSE
VFPTKVRYTASAVTYNISYALFGGTAPFIATYLIDVTGNILAPAIYITALAGLAFIAAWL
LPETAGRPLDGLDQPVGAPQPSRARLSVQ