Protein Info for DvMF_3204 in Desulfovibrio vulgaris Miyazaki F

Annotation: Holliday junction DNA helicase RuvA (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 202 TIGR00084: Holliday junction DNA helicase RuvA" amino acids 1 to 198 (198 residues), 118.9 bits, see alignment E=1e-38 PF01330: RuvA_N" amino acids 1 to 63 (63 residues), 64.3 bits, see alignment E=1.4e-21 PF14520: HHH_5" amino acids 73 to 130 (58 residues), 46.6 bits, see alignment E=5.7e-16 PF07499: RuvA_C" amino acids 155 to 199 (45 residues), 37.2 bits, see alignment 5e-13

Best Hits

Swiss-Prot: 100% identical to RUVA_DESVM: Holliday junction ATP-dependent DNA helicase RuvA (ruvA) from Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637)

KEGG orthology group: K03550, holliday junction DNA helicase RuvA (inferred from 100% identity to dvm:DvMF_3204)

Predicted SEED Role

"Holliday junction DNA helicase RuvA" in subsystem DNA-replication or RuvABC plus a hypothetical

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DNJ8 at UniProt or InterPro

Protein Sequence (202 amino acids)

>DvMF_3204 Holliday junction DNA helicase RuvA (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MIAYVEGRVAEISGNACVVVTEGGVGYEVHLPAHTLSRLPERGGQVAFHVRTEVREDALE
LFGFSTWDERQTFMVLTTISKVGARTALAILSQFRPDDLRRLVVEDDVLALTRVSGIGKK
TAQHIFLELKYKLKVEDLPAGLVLAGGAAPGGVFRDALAGLGNLGYLEDEAAPVLKEVLK
AEPDLDVAGALRAALKALARGR