Protein Info for DvMF_3111 in Desulfovibrio vulgaris Miyazaki F

Annotation: MATE efflux family protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 489 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details amino acids 62 to 85 (24 residues), see Phobius details amino acids 99 to 127 (29 residues), see Phobius details amino acids 139 to 161 (23 residues), see Phobius details amino acids 172 to 193 (22 residues), see Phobius details amino acids 199 to 223 (25 residues), see Phobius details amino acids 250 to 273 (24 residues), see Phobius details amino acids 285 to 308 (24 residues), see Phobius details amino acids 329 to 350 (22 residues), see Phobius details amino acids 370 to 394 (25 residues), see Phobius details amino acids 406 to 425 (20 residues), see Phobius details amino acids 437 to 456 (20 residues), see Phobius details PF01554: MatE" amino acids 28 to 186 (159 residues), 75 bits, see alignment E=5.7e-25 amino acids 253 to 418 (166 residues), 77.5 bits, see alignment E=1e-25 TIGR00797: MATE efflux family protein" amino acids 28 to 427 (400 residues), 178.5 bits, see alignment E=1e-56 PF14667: Polysacc_synt_C" amino acids 141 to 218 (78 residues), 29 bits, see alignment E=1.1e-10

Best Hits

KEGG orthology group: K03327, multidrug resistance protein, MATE family (inferred from 100% identity to dvm:DvMF_3111)

Predicted SEED Role

"Multidrug and toxin extrusion (MATE) family efflux pump YdhE/NorM, homolog"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DJH0 at UniProt or InterPro

Protein Sequence (489 amino acids)

>DvMF_3111 MATE efflux family protein (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MLSKMKTAATGRWSAPGGYREVLGVSLPLVAGMASTTVMEFTDRLFLSHYSVEAIAAATP
AAVVHLLFLLTCMGITGYAGVFIAQYIGSGAPHRVGVALWQGLLMAFFFGGCLALLWFAA
PAIFAFAGHLPAVQAGEVAYFRMLALGSVLALGNSCLGGFFSGQGRTRPVMLANFAAMAV
HIPLDYALIYGAWGLPEMGIAGAGLSMILSWAVTSLLLGGMVFTRRNERCFRVWSGRGFE
RALFLRMARYGLPSGINGFAELFSVTWFVFLVGELGETALAATNITFSINMVAFLPMMGM
NIAVGSMVGQAMGKGSPVAAERVTSSTLHVAMAWMLLLSLFFFCTPGPLYDLFLSGGAQD
PAVLAQKAEIRAMGVVLLRFVAVYCLLDAVTIVYTGALKGAGDTWFVMWNVLLGCVVWLV
LPTLALRASGLMTLNTLWAAFTAFILLLAVVSWLRFRRGAWKRLRLVETAHPLPDVPDGS
VGPEDGGKA