Protein Info for DvMF_3102 in Desulfovibrio vulgaris Miyazaki F

Annotation: putative glycerol-3-phosphate acyltransferase PlsX (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 346 PF02504: FA_synthesis" amino acids 7 to 327 (321 residues), 355.7 bits, see alignment E=2.2e-110 TIGR00182: fatty acid/phospholipid synthesis protein PlsX" amino acids 7 to 334 (328 residues), 365.2 bits, see alignment E=1.7e-113

Best Hits

Swiss-Prot: 84% identical to PLSX_DESVH: Phosphate acyltransferase (plsX) from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)

KEGG orthology group: K03621, glycerol-3-phosphate acyltransferase PlsX [EC: 2.3.1.15] (inferred from 100% identity to dvm:DvMF_3102)

Predicted SEED Role

"Phosphate:acyl-ACP acyltransferase PlsX" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.15

Use Curated BLAST to search for 2.3.1.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DJG2 at UniProt or InterPro

Protein Sequence (346 amino acids)

>DvMF_3102 putative glycerol-3-phosphate acyltransferase PlsX (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MNNATIIAVDAMGGDFGPSVVVPGAIEAARDKGIALLLVGDQAKVQAELARIPLDGVAYD
VVHASEVAGMDEKPSDILRRRKDASIQVACRLVRDGQAHGIVSAGHSGATVACGMFIMGR
IPGVDRPALATIMPTEKNPIVLLDVGANVDCKPHHLFQFGLMADAFARDLLSCESPRIGL
LSIGEEEGKGNTQVKEAYELFKLAQNGINFVGNVEGRDIFSGDVDVVVCDGFVGNVALKL
SEGLSTSLGRVLKRELLSGLLPKIGTLLAKSAFRRFAQFVDYAEYGGAPLLGLQGIAFVC
HGKSNSKAVCNAVKLAATFVEKKTNERLVKAISANEELTRYGKAIK