Protein Info for DvMF_3078 in Desulfovibrio vulgaris Miyazaki F

Name: mazG
Annotation: nucleoside triphosphate pyrophosphohydrolase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00444: MazG family protein
  • amino acids 20 to 282 (263 residues), 219.7 bits, E=2.4e-69
• PF03819: MazG
  • amino acids 36 to 109 (74 residues), 78.7 bits, E=3.2e-26

Best Hits

KEGG orthology group: K02428, nucleoside-triphosphate pyrophosphatase [EC: 3.6.1.19] (inferred from 100% identity to dvm:DvMF_3078)

Predicted SEED Role

"Nucleoside triphosphate pyrophosphohydrolase MazG (EC 3.6.1.8)" (EC 3.6.1.8)

KEGG Metabolic Maps

• Drug metabolism - other enzymes
• Purine metabolism
• Pyrimidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.19 or 3.6.1.8

Sequence Analysis Tools

See B8DJD8 at UniProt or InterPro

Protein Sequence (287 amino acids)

>DvMF_3078 nucleoside triphosphate pyrophosphohydrolase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MSTEPASPNSPHSLQAITDVIDRLLAPEGCPWDREQTPESLADYVIEECFELVEAIRSGK
VHDVREELGDVMFLLAFIGRLYADKGAFTLADAVEGNAAKMIRRHPHVFAEGECASREEL
LRNWERIKREEKAAAMAEDADAEGEAQAAPAEGAQKGVFDSLPKGLPPLVKAYRLHSKAA
RVDFTWESDEDVEQQVEAEWLEWLDASASGDKERQEQELGDFLFTIVELGRRKGIKANAA
LDYATLKFLRRFEGMEALARERGLDFPNLPFEGKDALWNEVKAAEKA