Protein Info for DvMF_2925 in Desulfovibrio vulgaris Miyazaki F

Annotation: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 PF01557: FAA_hydrolase" amino acids 50 to 245 (196 residues), 235.9 bits, see alignment E=2.2e-74

Best Hits

Swiss-Prot: 51% identical to Y2225_ARCFU: Uncharacterized protein AF_2225 (AF_2225) from Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_2925)

Predicted SEED Role

"5-carboxymethyl-2-hydroxymuconate delta-isomerase( EC:5.3.3.10 )"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DSA7 at UniProt or InterPro

Protein Sequence (260 amino acids)

>DvMF_2925 5-carboxymethyl-2-hydroxymuconate Delta-isomerase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MRVVRVQYKGSVFFGALQDDGVVCLNHQLGLKDPIPLADLAILPVVAPSKIICAGMNYRD
HAAEIGFPVPDEPVFFLKAPTAVIGSGQPILVPQGVGRVDYEGELAIVVGRQCRNISPDA
VPAHVFGYTCANDVTARDQQRRDGLFGRCKGYDTFCPVGPWIETDLPDTASLAVRTLVNG
EVRQQGNTADMLFTPNEMVSAISRVMTLLPGDLILTGTPVGVGPIVPGDEVRVEIEQVGL
LINPVLTAPDGDEHAEVPLQ