Protein Info for DvMF_2772 in Desulfovibrio vulgaris Miyazaki F

Annotation: signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 812 transmembrane" amino acids 35 to 56 (22 residues), see Phobius details amino acids 293 to 316 (24 residues), see Phobius details PF02743: dCache_1" amino acids 62 to 281 (220 residues), 45.3 bits, see alignment E=2.4e-15 TIGR00229: PAS domain S-box protein" amino acids 380 to 501 (122 residues), 23.7 bits, see alignment E=2.2e-09 PF13188: PAS_8" amino acids 381 to 435 (55 residues), 29.7 bits, see alignment 1.3e-10 PF00989: PAS" amino acids 382 to 450 (69 residues), 22.7 bits, see alignment E=2.5e-08 PF08448: PAS_4" amino acids 387 to 495 (109 residues), 32.5 bits, see alignment E=2.6e-11 PF00512: HisKA" amino acids 512 to 596 (85 residues), 28.8 bits, see alignment E=3.1e-10 PF02518: HATPase_c" amino acids 649 to 795 (147 residues), 79.1 bits, see alignment E=1.1e-25

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_2772)

Predicted SEED Role

"sensory box histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DJ49 at UniProt or InterPro

Protein Sequence (812 amino acids)

>DvMF_2772 signal transduction histidine kinase, nitrogen specific, NtrB (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MNVPITTPGGQPRAGVQKPPGHAPRSLRRLLHLRLLVWLVLLGLCILAFAGTFTYLGRKA
DFERQSALLTTTLARYLEEHVDNAALSLARLASALPASPSPARVAEELGRRRSLRQHFAR
IMLLDEAQRVVFSLPDGPVMVDFPVLRDPQGNGMGGRGYRLGSPAPLPDTGEVVVYVSEA
IEGGWQLVGALRLNTLQEHVLELLPGDDNAVLLADGYGNLIAHPDLTRVQRQENIGRLPF
FRPVGAVARNVEPTVQRVRYDDETWFACTAMVTGPDWTIITLKRQGAVLSEVAGEMVIFL
LLLTVLLTVFGVSLLAELEWTIARPLAGFCQSIRLVSGGSYDLPPSGGEQLAELADVDRE
FRDMAATVRQREAALRRTRAYVQQMMDAMPSAIVALDGHGRVVRMNPAALRRTGHAVTPA
GTPLSELLPDHADIAARLTAAMARRTPVDRERLVTLHGGHYRYEDVSLYPMGSGMTGAPE
GDGGVLRIDDVTDRVRMEEVLVQSEKMLSVGGLAAGMAHEINNPLGAILQGAQNIQRRLA
DGLPANEQAAERLGCSLPVIRAYLEERRVLEFLDSIREAGCRAANIITNMLEFSRNSGAR
RTTVDLHALLDRTLDIAASDYDLKKRYDFRNITIVREYEAELPPVVCSEQEITQVVLNLL
RNAAQAIAARSGNERPESLRPDGARPAGEGTEGAAAYAPSAPSGETGWDEPRIVLRTRRE
GAWMRIDVQDNGTGMPEDVRRRVFEPFFTTKEVGVGTGLGLSVSYFIVTRNHGGTFDVAS
EPGRGTTFTLRLPLPGSDQAPEVPRDHPGCPV