Protein Info for DvMF_2529 in Desulfovibrio vulgaris Miyazaki F

Annotation: MscS Mechanosensitive ion channel (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 864 signal peptide" amino acids 1 to 47 (47 residues), see Phobius details transmembrane" amino acids 287 to 309 (23 residues), see Phobius details amino acids 330 to 346 (17 residues), see Phobius details amino acids 353 to 374 (22 residues), see Phobius details amino acids 386 to 404 (19 residues), see Phobius details amino acids 410 to 428 (19 residues), see Phobius details amino acids 441 to 462 (22 residues), see Phobius details amino acids 468 to 492 (25 residues), see Phobius details amino acids 504 to 529 (26 residues), see Phobius details amino acids 559 to 580 (22 residues), see Phobius details amino acids 601 to 630 (30 residues), see Phobius details amino acids 632 to 632 (1 residues), see Phobius details amino acids 634 to 655 (22 residues), see Phobius details PF21088: MS_channel_1st" amino acids 601 to 641 (41 residues), 25.4 bits, see alignment 1.7e-09 PF00924: MS_channel_2nd" amino acids 642 to 709 (68 residues), 70.8 bits, see alignment 1.3e-23 PF21082: MS_channel_3rd" amino acids 718 to 799 (82 residues), 74.1 bits, see alignment E=1.5e-24

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_2529)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DQZ0 at UniProt or InterPro

Protein Sequence (864 amino acids)

>DvMF_2529 MscS Mechanosensitive ion channel (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MLHAPIRLPLRSPRRLTMLLALLGLAALAGLAPAGSGLPAPRAALAAQATAQAADAALPG
DTQQDAPDGQQAMDIIWQTRGQELSTLVEETDRLRKALPDMVKALDSQVAAMQRDYQRLF
ALYQLSRNHPSEMAAIRRQMAGVQRTLQGRLAPMEATDAAVRQRLDDFTALDKELSEHLA
TERSSDLSKDLSEYLAKLNEGRKNLTTLRTRLARALDPGQAVNAKLTQALEQIDAQLPTL
WRTYYLVASSSLMDLGVWLSLPANLAAWSDTTEIRLATEFPQSARDWGALLLRFAFLVVP
LFLLGRLALQRGCRLPGGWADSCRNVAARSWPWIAVGIALHFASWARGGEVYRAVVVPAH
LLLLWGELTLVWSLRAAGLAGVPQRSPLSLLFAPAAIGVLLLFLNPPAVLLAPLWALCMV
AVLAVRARRGRPRVLPLLEKVLLACEPALCIISLLAAVFGWARLAIPFFLVGLAVAVALQ
LGAVLVALVTLLAERLPEKGMRALLRGLVLGLGAPAMWVVAAATLLPWMSAFPGGPYMMR
QALELNVNVGSVSFNSLRVLGLVLLFYLTRSAIAVGTSFLDNLPARLPRVERGVIPPLQT
GLTYALWALFGLVVLNALGVSLTSLTVIAGGLSVGLGFGLQTIFNNFFSGLILIFGRSLL
EGDIIQIGETWGTVRKISIRSTTVETFDNAVIFVPNSEFVSNRLTNWTRNSMRMRRDIAI
GVAYGSDIDKVTELLKQAAEDHPRVMRDPAPNVLFQDFGPSSLDFVLRVWVDDLNHGVST
ASDLRRTIDRLFRENAIEISFPQMDVHVRGIEGMPVSTAALASPDPGPVEGAAAPRDTTE
SRTAPTSSSGNPGPKKDEDTRSET