Protein Info for DvMF_2220 in Desulfovibrio vulgaris Miyazaki F

Annotation: lipolytic protein G-D-S-L family (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 214 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00657: Lipase_GDSL" amino acids 31 to 198 (168 residues), 66.7 bits, see alignment E=3.3e-22 PF13472: Lipase_GDSL_2" amino acids 33 to 193 (161 residues), 102.6 bits, see alignment E=3.8e-33

Best Hits

Swiss-Prot: 38% identical to ESTE_VIBMI: Arylesterase from Vibrio mimicus

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_2220)

Predicted SEED Role

"Arylesterase precursor (EC 3.1.1.2)" (EC 3.1.1.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.2

Use Curated BLAST to search for 3.1.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DQP4 at UniProt or InterPro

Protein Sequence (214 amino acids)

>DvMF_2220 lipolytic protein G-D-S-L family (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MLVALTGLGLALLPSSTALAASGGNSSIPHILVLGDSLVAGYGLGPDEAFPERLGAALRA
KGRPARITNAGVSGDTSAGGLARVEWSLADKPDLLILELGANDGLRGLPVDDLRRNLAAI
VEICRKNGVRVLLAGMRAPLNMGAEYARRFDAVYPELAKQYGLTLYPFFLDGVALDRALN
LPDGMHPNPQGVQVIVERMLPVVERELDVLQARN