Protein Info for DvMF_2040 in Desulfovibrio vulgaris Miyazaki F

Annotation: methionyl-tRNA formyltransferase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 369 TIGR00460: methionyl-tRNA formyltransferase" amino acids 36 to 357 (322 residues), 280.2 bits, see alignment E=1e-87 PF00551: Formyl_trans_N" amino acids 37 to 214 (178 residues), 137.7 bits, see alignment E=3.8e-44 PF02911: Formyl_trans_C" amino acids 239 to 355 (117 residues), 82 bits, see alignment E=3.1e-27

Best Hits

KEGG orthology group: K00604, methionyl-tRNA formyltransferase [EC: 2.1.2.9] (inferred from 100% identity to dvm:DvMF_2040)

Predicted SEED Role

"Methionyl-tRNA formyltransferase (EC 2.1.2.9)" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase or Folate Biosynthesis (EC 2.1.2.9)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DMM7 at UniProt or InterPro

Protein Sequence (369 amino acids)

>DvMF_2040 methionyl-tRNA formyltransferase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MTGQDAVHADGAMPDCNGNTDAARVVTEPAAPRAPLRVVFMGTPGFAAVIMRHLLEWDGC
EVIAAYTQPDRPCGRGQQCRPPEVKLLAMEHGVPVYQPLNFKTEEAVAELRSLRPDVLVV
AAYGLILPQSVLDIPRLGPVNVHASLLPRLRGAAPIQRAVMAGDAVTGVTIMRMEASLDT
GPMLLQKAMGIDINDTAGDLHDQLAELGGRLLTVALGKLADGTAVAIPQDHDRATYAAKL
TKADGLIDWNRPAAQVHAHIRGVTPWPGAYCTIQRQSQGLQGGTVQKELRVSLGPGRFGP
LRSEAPEYDGAAPGTIVGLVDEQLAIACADRLYLVDSIRPADRKPMDARAFLCGYLNACE
CDGGLAVCV