Protein Info for DvMF_2022 in Desulfovibrio vulgaris Miyazaki F

Annotation: transcriptional regulator, GntR family with aminotransferase domain (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 593 PF00392: GntR" amino acids 12 to 75 (64 residues), 65.6 bits, see alignment E=2.6e-22 PF00155: Aminotran_1_2" amino acids 170 to 300 (131 residues), 20.6 bits, see alignment E=2.3e-08

Best Hits

KEGG orthology group: K00375, GntR family transcriptional regulator / MocR family aminotransferase (inferred from 100% identity to dvm:DvMF_2022)

Predicted SEED Role

"Predicted transcriptional regulator of pyridoxine metabolism" in subsystem Pyridoxin (Vitamin B6) Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DMK9 at UniProt or InterPro

Protein Sequence (593 amino acids)

>DvMF_2022 transcriptional regulator, GntR family with aminotransferase domain (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MFILNHEDSAPLYVQLYTQIRDRVLTGELPAGTRLPSVRHLADELGVSRNTVDTAYLELI
AEGFLLTRPRSGFFVAPVERHQAFRAGMPTTPAAAGAGPRRHPTTSDALGGSGTAGILGT
PDVTGAAHDRMHNRTHGGAHDRMHGAAAPSPYRFDFHPARLDPASFPLPLWRAYTLECLR
EAPRELSEYNHPQGDPELRRAIGDYLQRSRGVVCTPDRVIVCAGLQHSLEIVADIMMHAS
PNAGAGAVAGAVAGANPARPLVVGVENPGYPLPRAVFRNRGIPVVPVPVGPEGMDVDALA
QSRCTLAYVTPSHQFPLGHVMPVRNRLRLIQWANAGGNVIIEDDYDSELRYAGTPVPCMQ
GLHPGDAGRQAGPDNPAGPAGPAGSDKPNGQDSPDGLDGAVVYTGTFSKILSPALRMSYM
VLPPALLQVYRQRHRHHHAMVPLLEQRVLARFMARGHWDRHVRRMRTVYRQRHDAMLRAI
DTHFGGRATVIGQGAGLHVVVRLHGTDADERELALRAGRAGIRLLPFSETRLTDNPEAFR
GGPPASPPASAPHGYGNTSNDGPLLLLGFGGMPPDELEQGVAQLHRACFPRAR