Protein Info for DvMF_1938 in Desulfovibrio vulgaris Miyazaki F

Annotation: DNA polymerase III, delta prime subunit, putative (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 PF13177: DNA_pol3_delta2" amino acids 56 to 202 (147 residues), 92 bits, see alignment E=2.1e-30

Best Hits

KEGG orthology group: K02341, DNA polymerase III subunit delta' [EC: 2.7.7.7] (inferred from 100% identity to dvm:DvMF_1938)

Predicted SEED Role

"DNA polymerase III delta prime subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DQ17 at UniProt or InterPro

Protein Sequence (321 amino acids)

>DvMF_1938 DNA polymerase III, delta prime subunit, putative (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MANDTTTAPKRGRSAAAATDAPPAPQDPREVVAPLLDPRHRRTVGHLHALAASPPQVVLA
EGGTAPERMALALYWAALLNCEAPDDTPDDARPCLTCPSCLRMAGGGHRDLVVLDGNKPS
AEEGSFSIENVRALRGLLGEPPREGRRRVVVLVDAHTRVEAANGLLKSLEEPRPTTCFVL
LAPQRERLLPTLVSRSFVLTLAWPTDAAPPSPAVRDWLDALVEFIQTGGGWMERTSRKGD
LDAPLAAAVVLHCQRTLADVLAGRAADPLGRLLAERMDLARLRRCDEALAAAQEALSLSP
SPVNPALVMDWLATRMFLGVR