Protein Info for DvMF_1706 in Desulfovibrio vulgaris Miyazaki F

Annotation: glucosamine/fructose-6-phosphate aminotransferase, isomerizing (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01135: glutamine-fructose-6-phosphate transaminase (isomerizing)
  • amino acids 2 to 607 (606 residues), 766.1 bits, E=1.3e-234
• PF13522: GATase_6
  • amino acids 67 to 192 (126 residues), 71.7 bits, E=9.5e-24
• PF13537: GATase_7
  • amino acids 74 to 200 (127 residues), 55 bits, E=1.2e-18
• PF01380: SIS
  • amino acids 294 to 416 (123 residues), 113.4 bits, E=9.9e-37
  • amino acids 463 to 550 (88 residues), 62.2 bits, E=6.8e-21

Best Hits

KEGG orthology group: K00820, glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC: 2.6.1.16] (inferred from 100% identity to dvm:DvMF_1706)

Predicted SEED Role

"Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16)" in subsystem Sialic Acid Metabolism or UDP-N-acetylmuramate from Fructose-6-phosphate Biosynthesis (EC 2.6.1.16)

MetaCyc Pathways

• O-antigen building blocks biosynthesis (E. coli) (10/11 steps found)
• UDP-N-acetyl-D-glucosamine biosynthesis I (5/5 steps found)
• UDP-N-acetyl-D-glucosamine biosynthesis II (4/6 steps found)
• chitin biosynthesis (5/9 steps found)
• UDP-N-acetyl-D-galactosamine biosynthesis III (2/6 steps found)
• CMP-legionaminate biosynthesis I (2/10 steps found)
• superpathway of UDP-N-acetylglucosamine-derived O-antigen building blocks biosynthesis (8/24 steps found)
• superpathway of mycolyl-arabinogalactan-peptidoglycan complex biosynthesis (12/33 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Glutamate metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.16

Sequence Analysis Tools

See B8DM08 at UniProt or InterPro

Protein Sequence (607 amino acids)

>DvMF_1706 glucosamine/fructose-6-phosphate aminotransferase, isomerizing (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MCGIIGYAGHRPAVPLIIEGLRRLEYRGYDSAGVAFVQNRELITVRAEGKLSALDEKLAS
CPNTVATTGMGHTRWATHGIPVERNAHPHKSNDGGLAIVHNGIIENYAELKADLAAKGYV
FHSETDTEVLANLISEGRKHNATMLDAFAWALRQAHGAYAVALTTPEEPEVLYAARLSAP
LILGVGTGENFVASDIPAFLPYTRDVVFLEDGELVRIDANSWKVMRIADLSPVEKAVNHI
QWDMQAAQKGGYKHFMLKEIFEQPKVITDCLAGRVDWNRMEVTLPELAALPVPKRLHIVA
CGTSYHAGMWGKHLLESWARVPVNVEIASEFRYRDIILDPADMVLVISQSGETADTLAAL
RIAREHGVKVAGLCNVVGSSIAREADAVIYTQAGPEISVASTKAMCSQMVLLTLMALHWG
RNTGALSETVRANVLQTLRKLPGQLETVLPAMRDEAQVLARTYSKAKSFFYLGRGHCFPL
ALEGALKLKEISYIHAEGYASGEMKHGPIALIDPDFPTFALALNDELFPKVKSNIEEVQA
RRGKIIALTNPGVELKVDHPWSIPDAWGPMAAFLVLPALQLFSYEAADYLGKDVDQPRNL
AKSVTVE