Protein Info for DvMF_1553 in Desulfovibrio vulgaris Miyazaki F
Annotation: sulfite reductase, dissimilatory-type alpha subunit (RefSeq)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 90% identical to DSVA_DESVH: Sulfite reductase, dissimilatory-type subunit alpha (dsvA) from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)
KEGG orthology group: K11180, sulfite reductase, dissimilatory-type alpha subunit [EC: 1.8.99.3] (inferred from 100% identity to dvm:DvMF_1553)MetaCyc: 90% identical to dissimilatory sulfite reductase alpha subunit (Desulfovibrio vulgaris)
1.8.1.g [EC: 1.8.1.g]
Predicted SEED Role
"Dissimilatory sulfite reductase, alpha subunit (EC 1.8.99.3)" (EC 1.8.99.3)
MetaCyc Pathways
- dissimilatory sulfate reduction I (to hydrogen sufide)) (5/5 steps found)
- superpathway of thiosulfate metabolism (Desulfovibrio sulfodismutans) (4/6 steps found)
- superpathway of tetrathionate reduction (Salmonella typhimurium) (2/4 steps found)
- sulfur oxidation IV (intracellular sulfur) (2/7 steps found)
- superpathway of sulfide oxidation (phototrophic sulfur bacteria) (4/12 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.8.99.3
Use Curated BLAST to search for 1.8.1.g or 1.8.99.3
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See B8DRW2 at UniProt or InterPro
Protein Sequence (437 amino acids)
>DvMF_1553 sulfite reductase, dissimilatory-type alpha subunit (RefSeq) (Desulfovibrio vulgaris Miyazaki F) MAKHATPKLDQLESGPWPSFVSDIKQEAAYRAANPKGLDYQIPVDCPEDLLGVLELSYNE GETHWKHGGIVGVFGYGGGVIGRYCDQPEQFPGVAHFHTVRVNQPAAKYYHTDYLRQLCD LWDLRGSGLTNMHGSTGDIVLLGTQTPQLEELFFELTHKMNTDLGGSGSNLRTPESCLGM SRCEYACYDTQACCYALTMEYQDELHRPAFPYKFKFKFDGCPNGCVASIARSDFSVIGTW KDDIKIDQAAVKAYVGGELKPNAGAHSGRDWGKFDIMAEVVERCPSKCISWNGSALSIKT SECVRCMHCINTMPRALRIGDERGASILVGAKAPVLDGAQMGSLLVPFVDASEPFDEIKG VVEKIWDWWMEEGKNRERLGETIKRLSFQKLLEVTEIDPVAQHVKEPRSNPYIFFKEEEV PGGWDRDITEYRKRHQR