Protein Info for DvMF_1188 in Desulfovibrio vulgaris Miyazaki F

Annotation: Radical SAM domain protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 387 TIGR03700: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family" amino acids 17 to 367 (351 residues), 507.5 bits, see alignment E=1.6e-156 TIGR00423: radical SAM domain protein, CofH subfamily" amino acids 59 to 365 (307 residues), 351.4 bits, see alignment E=4.5e-109 PF04055: Radical_SAM" amino acids 66 to 237 (172 residues), 63.8 bits, see alignment E=2.3e-21 PF19288: CofH_C" amino acids 249 to 370 (122 residues), 68 bits, see alignment E=7.3e-23

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_1188)

Predicted SEED Role

"Gene SCO4494, often clustered with other genes in menaquinone via futalosine pathway" in subsystem Menaquinone Biosynthesis via Futalosine

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DKH8 at UniProt or InterPro

Protein Sequence (387 amino acids)

>DvMF_1188 Radical SAM domain protein (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MLDAAHYARLGLGIAFEKVMEGARLSPEEGLALFHCPDITAVGALAHHARTRLHGDRTYY
VLNRHVNYTNICVNGCLFCAFQRERGQAGSFALTPDDILHRVLDDRGTPFSEVHIVGGCH
PDLGLAWFEDVIRRIRKARPQSIVKAFTGVEIAHFAAMEGISTLDVLRRLQDAGLAMMPG
GGAEIFAPEVRTRICPRKATADEWLRVAGEAHSLGIRTNCSMLYGHIETFEHRVDHLCRL
REQQDKSGGFTCFIPLPFLTENSLLKLPPERVGEHVGLDRLRTVAVSRLMLDNIPHVKAY
WVMMGVKMAQTALYFGADDLDGTIVEERIGHDAGADSAQSLTVPELELMIRRSGFTPVRR
DSHFNPVADPDAIRNDAGHAATPEVRA