Protein Info for DvMF_1148 in Desulfovibrio vulgaris Miyazaki F

Annotation: TrkA-N domain protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 614 transmembrane" amino acids 23 to 46 (24 residues), see Phobius details amino acids 58 to 76 (19 residues), see Phobius details amino acids 84 to 109 (26 residues), see Phobius details PF07885: Ion_trans_2" amino acids 32 to 100 (69 residues), 38.5 bits, see alignment E=2.1e-13 PF02254: TrkA_N" amino acids 133 to 245 (113 residues), 49.1 bits, see alignment E=1.7e-16 amino acids 400 to 510 (111 residues), 85.3 bits, see alignment E=9.8e-28 PF02080: TrkA_C" amino acids 285 to 346 (62 residues), 42.8 bits, see alignment E=9.5e-15 amino acids 538 to 603 (66 residues), 42.8 bits, see alignment E=9.6e-15 PF01494: FAD_binding_3" amino acids 397 to 458 (62 residues), 23.9 bits, see alignment E=5.7e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_1148)

Predicted SEED Role

"Trk system potassium uptake protein TrkA" in subsystem Bacterial RNA-metabolizing Zn-dependent hydrolases or Conserved gene cluster associated with Met-tRNA formyltransferase or Glutathione-regulated potassium-efflux system and associated functions or Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DKE0 at UniProt or InterPro

Protein Sequence (614 amino acids)

>DvMF_1148 TrkA-N domain protein (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MKFLPSQIAFFMQSRSAQRNMRFLFRFVLLLVAVITLYSVLFHVIMDYEGRDYSWATGFY
WTLTVMSTLGFGDITFLSDTGKLFTLVVLLSGIIFLLVMLPFTFIQFFYAPWLEAQTRLR
APRELPAETRDHVIIVGGDATALGLGRDLAQYAHPYVLLCADAQTALDLQDQGFSVAVGD
YDDPETYRRLRVEQAAMLVALDGDVRNTNVAFTAREASPGIPVVCGADQDEAVDILTMAG
GTHVFRFSSMLGQGLARRTLAGHMRTGVVGRFDDLVVAEAPVMRTGLVGHSLRDNDLRKV
TGVNVVGVWERGRFQLPRPDAPLEASTVLVLAGTRQQMDAFDRYIGGRGVNDAPGGAGGA
GPTGGAGMTGVTGEIGETGEAGRHDRAGGTSTSPASDTPVLILGGGRVGLAAARQFAETG
IDYRIVEKNPRLVHDNVHTITGSAADLDVLERAGIREAPAVLVTTHDDDLNIYLTIYCRR
LRPDIQIISRATLDRNIGILHKAGADLVMSHGSLVSNTVINLLNPGKVLMLSEGLNIFRA
PVGLGLAGRTLKDSGIRDETGCSVVALRGPGGLSVNPDPTLLLRACDELILIGDSEAERR
FLERYPDDEECEEA