Protein Info for DvMF_1096 in Desulfovibrio vulgaris Miyazaki F

Annotation: multi-sensor hybrid histidine kinase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1548 transmembrane" amino acids 15 to 35 (21 residues), see Phobius details amino acids 197 to 218 (22 residues), see Phobius details PF12729: 4HB_MCP_1" amino acids 13 to 182 (170 residues), 52.2 bits, see alignment E=3.7e-17 PF00672: HAMP" amino acids 214 to 261 (48 residues), 25.3 bits, see alignment (E = 1e-08) PF13185: GAF_2" amino acids 290 to 401 (112 residues), 29.6 bits, see alignment 4.7e-10 PF01590: GAF" amino acids 290 to 408 (119 residues), 25.3 bits, see alignment 1.3e-08 TIGR00229: PAS domain S-box protein" amino acids 454 to 523 (70 residues), 35.1 bits, see alignment 6.6e-13 amino acids 607 to 734 (128 residues), 83.3 bits, see alignment E=7.8e-28 PF13426: PAS_9" amino acids 480 to 597 (118 residues), 31.2 bits, see alignment 1.4e-10 amino acids 620 to 725 (106 residues), 52.8 bits, see alignment 2.7e-17 PF13188: PAS_8" amino acids 612 to 665 (54 residues), 38.2 bits, see alignment (E = 6.3e-13) PF00989: PAS" amino acids 612 to 724 (113 residues), 42.4 bits, see alignment 4.2e-14 PF08448: PAS_4" amino acids 617 to 729 (113 residues), 36.1 bits, see alignment 4.5e-12 PF00512: HisKA" amino acids 748 to 812 (65 residues), 76.6 bits, see alignment (E = 8.3e-25) PF02518: HATPase_c" amino acids 859 to 973 (115 residues), 89.3 bits, see alignment 1.6e-28 PF00072: Response_reg" amino acids 993 to 1105 (113 residues), 76.1 bits, see alignment 1.5e-24 amino acids 1140 to 1251 (112 residues), 97 bits, see alignment 5e-31 PF01627: Hpt" amino acids 1338 to 1418 (81 residues), 39.7 bits, see alignment 3.1e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_1096)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DK88 at UniProt or InterPro

Protein Sequence (1548 amino acids)

>DvMF_1096 multi-sensor hybrid histidine kinase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MPTPPGPMLFRHLSVFQRLLICTLLIVAFSIVLGYSTLSLMRDMAEDANTVYRHTFIATS
SLQQAKESVERMRAAMREQIIEVDEAIKAEQVATLRREERLFHDCVEAVRANFRGEPALI
DALASHYDDFLSMRDRAMTMSENREIQEAWRLTESSPQNPADRLLHAIDDLMHAARATAE
HFFQSSVAENRTTQLKAIAASGLFCAMVVAITYLVSWSIRRRLLALTGCVKALADGDLDV
QIPYGEERNEMGAMARSLQVLLGVSRQMEQQRWIKAQMSETATTLQQAGDLDSFGQRLSA
VAAQVSGAPYAALYVPNDDGVHLDLVASLGGIVGGPPASIPKGGGLVGRCAATRAPVELT
PPEGETLRFATGLGDVHPASLRAYPLLLGERLLGVLELATLGPLPPRAATLFEDMLPMAA
LSQEVLERNLHTRSLLDQTRRQATELEESRELLRRSEAFFRAVFETAGIGIVSERRGLGI
DRANPAFSDFIGISEPELRGRDLEDFFHPDDREALEALLSRLDPDKLEYAVPRHGNPERD
GLDAGEPDQARSTITVRAEHRYLRPDGEVRWADVRCALIGDRDITPRRVTLINDITELKE
QQAELKDTEAWYRGIVHSAPDAMVVVDGEGRIVLCNPQLERLLGYEMGELTGHLVEQFLP
EEVRERHVKLRNDFLASPLQVIGHEREVIGVRKDGTRLPLEISLSKLPPSDRHPMSACGA
LRDISLRKRSEAELRRAKEMAEEATRLKSDFLANMSHEIRTPMNAIIGMAHLALKTELDP
RQADYVRKIRASGQHLLGILNDILDFSKIEAGKLTVENTEFELETVLDTVANLVSEKAAT
KGLEFVLDVAANVPPVLRGDPLRLGQILINYANNAVKFTEHGEIVIHVETLETGDTDVLL
RFAVRDTGIGLTDEQKARLFVSFQQADTSTTRKYGGTGLGLAIAKKLADLMGGGVGVDSV
PGGGSTFWFTARLGLGSGRRALLPRIDLRGLRVLVVDDNPQARMVLAHMLEGMTFRPVMA
DGGETALDLLREARDADTPFGMVFLDWQMPGMDGLETARNIRTLAPDLPVAIVTAHGREE
IFAASEGVGVSAVLVKPVQPSLLFDTAMRLLGAVHPAPRAAVPPPDTRPAMLDGVRGSRV
LLVEDNELNREVALGLLAEAGLVPDAAEDGAQAVRMVMEGDYDLVLMDVQMPVMDGYEAT
RIIRRSREADSLPIVAMTANAMRSDREACLAAGMNDHVAKPIDPDELFAALIRWLPRRGE
AERQQDAADTTAPGTQPATQADTLSGASPDTSPASGPVRQHGQNGQGRQNGQNDARHVLD
PEAGLRRVLGKQATYHTLLRRFVSQHADAATRIAGFIQSGDGAGATREAHTLKGVAGTLG
ARAVQSQAADLEAALRHAASQEHTTEVLALLRISLDEAVRAMHRLLDATRPDPNGAAPGT
VPDAPVRRDAGSGDAAGDGHEAGQDTGPERNLADSDLSRALPEGLLDQLETLIEEDDSEA
VDLFNTHSEALRAALGQPLVTGMGEALRAFEFETALEMLRSARPPHDG